1410073-12-9

Basic information

• Product Name: 3-bromo-1-(3-chloropyridin-2-yl)-N-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
• Synonyms: 3-bromo-1-(3-chloropyridin-2-yl)-N-(4-nitrophenyl)-1H-pyrazole-5-carboxamide
• CAS NO: 1410073-12-9
• Molecular Weight: 422.625
• Mol File: 1410073-12-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-bromo-1-(3-chloropyridin-2-yl)-N-(4-nitrophenyl)-1H-pyrazole-5-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-1-(3-chloropyridin-2-yl)-N-(4-nitrophenyl)-1H-pyrazole-5-carboxamide(1410073-12-9)
• EPA Substance Registry System: 3-bromo-1-(3-chloropyridin-2-yl)-N-(4-nitrophenyl)-1H-pyrazole-5-carboxamide(1410073-12-9)

Safety Data

• Hazardous Substances Data: 1410073-12-9(Hazardous Substances Data)

Upstream product

• 500011-86-9 3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid 
• 500011-92-7 5-bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid ethyl ester 
• 500011-91-6 5-bromo-2-(3-chloro-pyridin-2-yl)-3,4-dihydro-2H-pyrazole-3-carboxylic acid ethyl ester 
• 500011-88-1 2-(3-chloro-pyridin-2-yl)-5-oxo-pyrazolidine-3-carboxylic acid ethyl ester 
• 943982-60-3 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carbonyl chloride 
• 100-01-6 4-nitro-aniline 
• 2402-77-9 2,3-dichloro-pyridine 
• 22841-92-5 (3-chloro-2-pyridyl)hydrazine 

Relevant articles and documents

Facile synthesis of pyrazolo[1,5-a]pyridopyrazin-one via Smiles rearrangement or direct cyclization

A facile access to pyrazolo[1,5-a]pyridopyrazin-one is presented via Smiles rearrangement or direct cyclization. The method allows the convenient construction of a novel biaryl lactam in moderate to excellent yields starting from easily available precursors (18 examples, 75-97% yield). When R is an aryl group, two regioisomeric products were obtained, Smiles rearrangement product and direct cyclization product, but when R is alkyl or benzyl, Smiles rearrangement product was afforded selectively. In order to prove the proposed mechanism, intermediate 6k was trapped.