141172-41-0Relevant articles and documents
Studies on pyrrolidinones: Some attempts to improve the anticancer properties of methyl N-(3,4,4′,5-tetramethoxybenzhydryl)pyroglutamate (HEI 81)
Bourry, Anne,Rigo, Benoit,Sanz, Gerard,Couturier, Daniel
, p. 119 - 124 (2002)
The synthesis of esters, amides, pyrrolidinone and succinimide analogs of a new inhibitor of tubulin polymerization, methyl N-(3,4,4′,5-tetramethoxybenzhydryl)pyroglutamate (HEI 81) was studied.
Isocombretastatins A: 1,1-Diarylethenes as potent inhibitors of tubulin polymerization and cytotoxic compounds
Alvarez, Raquel,Alvarez, Concepcion,Mollinedo, Faustino,Sierra, Beatriz G.,Medarde, Manuel,Pelaez, Rafael
experimental part, p. 6422 - 6431 (2011/02/24)
Isocombretastatins A are 1,1-diarylethene isomers of combretastatins A. We have synthesized the isomers of combretastatin A-4, deoxycombretastatin A-4, 3-amino-deoxycombretastatin A-4 (AVE-8063), naphthylcombretastatin and the N-methyl- and N-ethyl-5-indo
Stilbene derivatives as anticancer agents
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, (2008/06/13)
The present invention relates to stilbene derivatives which possess utility as anti-cancer agents. The compounds can be used to treat cancers which are susceptible to treatment therewith, and can be utilized in a method of treating such cancers. Pharmaceu