141289-30-7

Basic information

• Product Name: N-acetyl-DL-homophenylalanine ethyl ester
• Synonyms: N-acetyl-DL-homophenylalanine ethyl ester
• CAS NO: 141289-30-7
• Molecular Weight: 249.31
• Mol File: 141289-30-7.mol

Chemical Properties

• CAS DataBase Reference: N-acetyl-DL-homophenylalanine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-acetyl-DL-homophenylalanine ethyl ester(141289-30-7)
• EPA Substance Registry System: N-acetyl-DL-homophenylalanine ethyl ester(141289-30-7)

Safety Data

• Hazardous Substances Data: 141289-30-7(Hazardous Substances Data)

Upstream product

• 46460-23-5 ethyl L-2-amino-4-phenylbutyrate 
• 108-24-7 acetic anhydride 
• 103-63-9 1-phenyl-2-bromoethane 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 5463-92-3 2-acetylamino-2-phenylethylmalonic acid diethyl ester 
• 80887-22-5 2-Acetylamino-2-phenethyl-malonic acid monoethyl ester 

Downstream Products

• 96613-91-1 (R)-2-Acetamido-4-phenylbutansaeure 
• 27038-09-1 (2S)-2-amino-4-phenyl-1-butanol 
• 60425-49-2 (+)-α-amino-4-phenylbutyric acid methyl ester hydrochloride 
• 105382-09-0 L-(+)-homophenylalanine hydrochloride 

Relevant articles and documents

Resolution of N-protected amino acid esters using whole cells of Candida parapsilosis ATCC 7330

Whole cells of Candida parapsilosis ATCC 7330 were used for the resolution of N-acetyl amino acid esters. Excellent enantioselectivities (E = 40 to >500) were achieved for the resolution of N-protected protein and non-protein amino acid esters giving good yields (28-50%) and high enantiomeric excesses (up to >99%) for both enantiomers.

Concise synthesis and enzymatic resolution of L-(+)-homophenylalanine hydrochloride

The N-acetyl-homophenylalanine ethyl ester was synthesized by a simple three-step-reaction strategy. L-(+)-homophenylalanine hydrochloride with 98% ee was obtained through a kinetic resolution process using industrial enzyme alcalase. Compared with other

Variations of the Nature of the Chiral Auxiliary with a Highly Enantioselective Chiral NADH Model

Various chiral amine alcohols have been used as chiral auxiliares for a highly enantioselective NADH model.Some of these are new reagents which have been obtained by an enzymic resolution method.