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46460-23-5

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46460-23-5 Usage

Description

L-Homophenylalanine ethyl ester is a chemical compound derived from the amino acid phenylalanine, forming an ethyl ester with ethyl alcohol. It has been studied for its potential therapeutic applications, particularly in drug development, due to its neuroprotective properties and research interest in treating neurodegenerative disorders and cancer.

Uses

Used in Pharmaceutical Research:
L-Homophenylalanine ethyl ester is used as a potential therapeutic agent for its neuroprotective properties, primarily for the treatment of neurodegenerative disorders such as Parkinson's disease.
Used in Neurodegenerative Disorder Treatment:
In the field of neurology, L-Homophenylalanine ethyl ester is used as a potential treatment option aimed at protecting neurons and slowing the progression of neurodegenerative conditions.
Used in Cancer Treatment Research:
L-Homophenylalanine ethyl ester is used as a subject of research for its potential anti-tumor properties, with the aim of developing new cancer therapies.
Used in Drug Development:
In the pharmaceutical industry, L-Homophenylalanine ethyl ester is utilized as a compound of interest for the development of new drugs targeting various diseases, including neurodegenerative disorders and cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 46460-23-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,6,4,6 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 46460-23:
(7*4)+(6*6)+(5*4)+(4*6)+(3*0)+(2*2)+(1*3)=115
115 % 10 = 5
So 46460-23-5 is a valid CAS Registry Number.

46460-23-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl (2S)-2-amino-4-phenylbutanoate

1.2 Other means of identification

Product number -
Other names (RS)-homophenylalanine ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:46460-23-5 SDS

46460-23-5Relevant articles and documents

Site-Selective Modification of α-Amino Acids and Oligopeptides via Native Amine-Directed γ-C(sp3)-H Arylation

Yuan, Feipeng,Hou, Zhen-Lin,Pramanick, Pranab K.,Yao, Bo

supporting information, p. 9381 - 9385 (2019/11/28)

Site-selective modification of chemically and biologically valuable α-amino acids and peptides is of great importance for biochemical study and pharmaceutical development. Few methods based on remote C(sp3)-H functionalization of aliphatic side-chains of peptides has been disclosed in recent years. In this report, we developed a novel approach for γ-C(sp3)-H and γ-/δ-C(sp2)-H arylation of α-amino acids with α-hydrogen by native amine-directed C-H functionalization and further realized the γ-C(sp3)-H arylation of N-terminally unprotected peptides.

IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS

-

Page/Page column 64, (2018/11/22)

The present invention is in the field of bioluminescence in biology and/or medicine. In particular, the invention provides imidazopyrazine derivatives, processes for preparation thereof, and their uses as luciferins.

Kinetic study of the alkaline degradation of imidapril hydrochloride using a validated stability indicating HPLC method

Abdulla, Shabaan A.,Frag, Eman Y.,Ahmed, Heba E.

, p. 69239 - 69250 (2016/08/05)

An aqueous alkaline degradation study was performed for imidapril hydrochloride (IMD) drug in the presence of its degradation products and an isocratic stability indicating method was presented using a HPLC technique. The separations were performed using an ACE Generix 5C8, 150 × 4.6 mm column and a mobile phase consisting of buffer solution (0.1 M potassium dihydrogen phosphate and 0.02 M tetra-N-butyl ammonium hydrogen sulphate of pH = 4.5 with 1 N HCl) and acetonitrile 60:40 (v/v). The wavelength of the detector was adjusted at 210 nm. The method showed high sensitivity concerning accuracy, precision, linearity and specificity within the acceptable range from 0.1 to 100 μg mL-1 and the limit of quantification was found to be 0.0211 μg mL-1 for IMD. The proposed method was used to determine the drug in its pharmaceutical formulation and to investigate the degradation kinetics of the drug's alkaline-stressed sample. The reactions were found to follow a first-order reaction. The activation energy could also be estimated. The optimized stability indicating HPLC method was validated according to ICH guidelines.

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