141554-36-1Relevant articles and documents
An aldol - Bislactonization route to α-methylene bis-γ-butyrolactones
Lertvorachon, Jittiwud,Meepowpan, Puttinan,Thebtaranonth, Yodhathai
, p. 14341 - 14358 (2007/10/03)
The syntheses of α-methylene γ-butyrolactones and α-methylene bis- γ-butyrolactones are made simple through the use of the versatile dimethyl itaconate - anthracene adduct, 1.
High Diastereoselection in the Aldol Reaction of the Bistrimethylsilyl Enol Ether of Methyl Acetoacetate with 2-Benzyloxyhexanal: Synthesis of (-)-Pestalotin
Hagiwara, Hisahiro,Kimura, Katsuhiko,Uda, Hisashi
, p. 693 - 700 (2007/10/02)
Aldol condensation of the bistrimethylsilyl enol ether of methyl acetoacetate, compound 2, with 2-benzyloxyhexanal 3c affords highly selectively (99:1) the syn-aldol adduct 4c in the presence of titanium tetrachloride.The stereocontrolled synthesis of (-)-pestalotin 7 has been achieved.