14164-31-9

Basic information

• Product Name: 5-phenylpenta-2,4-dienenitrile
• CAS NO: 14164-31-9
• Molecular Formula: C₁₁H₉N
• Molecular Weight: 155.1959
• Mol File: 14164-31-9.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 305.4°C at 760 mmHg
• Flash Point: 138.9°C
• Density: 1.031g/cm³
• Vapor Pressure: 0.000825mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 5-phenylpenta-2,4-dienenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenylpenta-2,4-dienenitrile(14164-31-9)
• EPA Substance Registry System: 5-phenylpenta-2,4-dienenitrile(14164-31-9)

Safety Data

• Hazardous Substances Data: 14164-31-9(Hazardous Substances Data)

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 75-05-8 acetonitrile 
• 39806-16-1 ethyl (2E,4E)-5-phenyl-penta-2,4-dienoate 
• 100-52-7 benzaldehyde 
• 192886-57-0 (4E)-5-phenylpenta-2,4-dien-1-ol 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 4192-77-2 ethyl cinnamate 
• 773837-37-9 sodium cyanide 
• 24139-57-9 α-cyano-5-phenyl-2,4-pentadienic acid 
• 4364-06-1 (E)-cinnamaldehyde dimethylacetal 
• 104-54-1 3-Phenylpropenol 
• 4336-70-3 (cyanomethyl)triphenylphosphonium chloride 
• 1133296-08-8 C₁₄H₁₈OSi 
• 14604-31-0 (E)-1-phenylpent-1-en-4-yn-3-ol 

Downstream Products

• 28010-12-0 5-phenylpenta-2,4-dienoic acid 
• 13466-40-5 (2E, 4E)-5-phenylpenta-2,4-dienal 
• 100840-28-6 3-<(E)-2-phenylethenyl>-5-hexenenitrile 
• 829-97-0 5-phenyl-penta-2,4-dienoic acid amide 
• 100840-27-5 5-phenyl-3,7-octadienenitrile 

Relevant articles and documents

One-pot silyl ketene imine formation-nucleophilic addition reactions of acetonitrile with acetals and nitrones

Trimethylsilyl trifluoromethanesulfonate (TMSOTf) and a trialkylamine base promote the conversion of acetonitrile to its silyl ketene imine in situ when acetonitrile is employed as solvent. Residual TMSOTf acts as a Lewis acid catalyst to activate acetals

Development and Utilization of a Palladium-Catalyzed Dehydration of Primary Amides to Form Nitriles

A palladium(II) catalyst, in the presence of Selectfluor, enables the efficient and chemoselective transformation of primary amides into nitriles. The amides can be attached to aromatic rings, heteroaromatic rings, or aliphatic side chains, and the reactions tolerate steric bulk and electronic modification. Dehydration of a peptaibol containing three glutamine groups afforded structure-activity relationships for each glutamine residue. Thus, this dehydration can act similarly to an alanine scan for glutamines via synthetic mutation.

Preparation method of trans-alpha, beta-unsaturated nitriles compound

The invention relates to a preparation method of a trans-alpha, beta-unsaturated nitriles compound. The method comprises the following steps: uniformly mixing a benzyl alcohol compound, acetonitrile, a promoter and alkali, and carrying out reflux reaction completely to obtain reaction liquid; carrying out conventional extraction, drying, concentration and column chromatographic separation on the reaction liquid in sequence to obtain the trans-alpha, beta-unsaturated nitriles compound. The preparation method belongs to double-component one-boiler reaction, so that conditions are relatively mild, and raw materials are easy to prepare and readily available; the operation is simple, the yield is relatively high, and greenness, environment friendliness and economy can be realized; large-scale production can be realized; the preparation method has an extremely good application potential on the aspect of fine chemicals, and has a relatively good industrial application prospect.