142-94-9

Basic information

• Product Name: 2-BROMOSTEARIC ACID
• Synonyms: BROMONUCLEIC ACID;DL-ALPHA-BROMOSTEARIC ACID;ALPHA-BROMOSTEARIC ACID;2-BROMOSTEARIC ACID;2-BROMO-OCTADECANECARBOXYLIC ACID;2-BROMO-OCTADECANOIC ACID;2-BROMOSTEARIC ACID, TECH.;Octadecanoic acid,2-bromo-
• CAS NO: 142-94-9
• Molecular Formula: C₁₈H₃₅BrO₂
• Molecular Weight: 363.37
• EINECS: 205-573-2
• Product Categories: Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides
• Mol File: 142-94-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 58-60°C
• Boiling Point: 431 °C at 760 mmHg
• Flash Point: 214.5 °C
• Appearance: /
• Density: 1.088 g/cm³
• Vapor Pressure: 1.23E-08mmHg at 25°C
• Refractive Index: 1.479
• Storage Temp.: −20°C
• CAS DataBase Reference: 2-BROMOSTEARIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMOSTEARIC ACID(142-94-9)
• EPA Substance Registry System: 2-BROMOSTEARIC ACID(142-94-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 142-94-9(Hazardous Substances Data)

Usage

General Description

2-Bromostearic acid is a chemical compound belonging to the class of stearic acids that contains a bromine atom. It is commonly used in the production of specialty chemicals, pharmaceuticals, and as a component in surfactants and detergents. 2-BROMOSTEARIC ACID is notable for its ability to modify the physical and chemical properties of materials, making it useful in various industrial applications. 2-Bromostearic acid is also utilized in the synthesis of other organic compounds and can act as a precursor in the preparation of diverse chemical products. Its unique structure and reactivity make it an important building block in the manufacturing of a wide range of commercial and industrial products.

InChI:InChI=1/C18H35BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17(19)18(20)21/h17H,2-16H2,1H3,(H,20,21)/t17-/m0/s1

Upstream product

• 7726-95-6 bromine 
• 57-11-4 stearic acid 

Downstream Products

• 7217-83-6 2-methyl-octadecanoic acid 
• 5340-56-7 ethyl 2-bromostearoate 
• 5782-80-9 2-amino-octadecanoic acid 
• 111-61-5 stearic acid ethyl ester 
• 506-12-7 heptadecanoic acid 
• 629-90-3 n-heptadecanal 
• 7152-35-4 Diethyl-α-ethoxycarbonylheptadecylphosphonat 
• 67491-95-6 2-(2-Hydroxyethylamino)octadecanoic acid 
• 135147-10-3 5-Benzylsulfanyl-2-dimethylamino-4-hexadecyl-[1,3]dithiol-1-ylium; bromide 
• 14663-11-7 methyl trans-2-octadecenoate 
• 2420-35-1 2-hydroxyoctadecanoic acid methyl ester 
• 160147-98-8 (2S,2'R,3R,4E,8E)-N-2'-acetoxyoctadecanoyl-1-O-(β-D-glucopyranosyl)-3-O-(t-butyldiphenylsilyl)-9-methyl-4,8-sphingadienine 
• 113773-89-0 cerebroside 
• 160147-91-1 p-nitrophenyl (R)-2-acetoxyoctadecanoate 

Relevant articles and documents

Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents

A series of α- and β-carboxylated phospholipid prodrugs of dideoxy nucleosides have been synthesized and evaluated against HIV. An increase in biological effect with a factor of 500 has only been observed for the adenine nucleoside, which suggests that this prodrug approach is base specific.

Mesoionic 5-alkyl-1,3-dithiolium-4-thiolates: Synthesis and brine shrimp toxicity

A series of twelve 1,3-dithiolium-4-thiolate mesoionic compounds were synthesized and characterized. The synthetical approach starting from α-bromoalkanoic acids to obtain the corresponding 2-N-morpholino-dithiocarbamoyl-carboxylic acids that by on-pot reaction with carbon disulfide and acetic anhydride in triethylamine formed not isolate intermediates, 1,3-dithiolium-4-olates. After, the 2-N-morpholino-5-alkyl-1,3-dithiolium-4-thiolates were obtained by retro 1,3-dipolar addition reactions. The alkyl moiety linked to C-5 of heterocyclic ring permitted the increase of the hydrophobic character and this effect was evaluated on Artemia salina lethality. The results indicated a bell-shaped relationship between the number of carbon of side chain in mesoionic derivatives and LD50 in brine shrimp toxicity assays.

Synthesis of (2S,2'R,3R,4E,8E)-N-2'-Hydroxyoctadecanoyl-1-O-(β-D-glucopyranosyl)-9-methyl-4,8-sphingadienine (Pen III), a Cerebroside Isolated from Penicillium funiculosum as the Fruiting Inducer against Schizophyllum commune

(2S,2'R,3R,4E,8E)-N-2'-Hydroxyoctadecanoyl-1-O-(β-D-glucopyranosyl)-9-methyl-4,8-sphingadienine (Pen III), a cerebroside isolated from Penicillium funiculosum A-1 as the fruiting inducer against Basidiomycete Schizophyllum commune, was synthesized by starting from D-glucose, L-serine, homoprenyl acetate and stearic acid.