142102-79-2 Usage
Uses
Used in Antiviral Applications:
1-(2',5'-bis-O-(tert-butyldimethylsilylribofuranosyl)-3-N-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) is used as an antiviral agent for its potential to combat DNA viruses. 1-(2',5'-bis-O-(tert-butyldimethylsilylribofuranosyl)-3-N-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) works by inhibiting viral DNA replication, acting as a chain terminator during the synthesis process. This makes it a promising candidate for the development of new antiviral therapies.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(2',5'-bis-O-(tert-butyldimethylsilylribofuranosyl)-3-N-methylthymine)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) is used as a subject of research for understanding its mechanism of action and potential as an antiviral agent. Further studies are necessary to fully comprehend its capabilities and optimize its use in antiviral drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 142102-79-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,1,0 and 2 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 142102-79:
(8*1)+(7*4)+(6*2)+(5*1)+(4*0)+(3*2)+(2*7)+(1*9)=82
82 % 10 = 2
So 142102-79-2 is a valid CAS Registry Number.
142102-79-2Relevant academic research and scientific papers
TSAO derivatives: Highly specific inhibitors of human immunodeficiency virus type-1 (HIV-1) replication
Camarasa,Perez-Perez,Velazquez,San-Felix,Alvarez,Ingate,Jimeno,Karlsson,De Clercq,Balzarini
, p. 585 - 594 (2007/10/02)
TSAO derivatives represent a unique class of nucleosides that are specifically targeted at HIV-1 RT. This overview is focussed on the chemical synthesis, the conformational studies, the antiviral and metabolic properties of TSAO derivatives, as well as th
TSAO analogues. Stereospecific synthesis and anti-HIV-1 activity of 1- [2',5'-bis-O-(tert-butyldimethylsilyl)-β-D-ribofuranosyl]-3'-spiro-5''-(4''- amino-1'',2''-oxathiole 2'',2''-dioxide) pyrimidine and pyrimidine-modified nucleosides
Perez-Perez,San-Felix,Balzarini,De Clercq,Camarasa
, p. 2988 - 2995 (2007/10/02)
Several analogues of a new lead for anti-HIV-1 agents [1-[2',5'-bis-O- (tert-butyldimethylsilyl)-β-D-ribofuranosyl]-thymine]-3'-spiro-5''-(4''- amino-1'',2''-oxathiole 2'',2''-dioxide) (TSAO) modified at positions N-3, O- 4 and C-5 of the thymine moiety,
