1422447-32-2Relevant academic research and scientific papers
A Concise Synthesis of 2-(2-Hydroxyphenyl)acetonitriles via the o-Quinone Methides Generated from 2-(1-Tosylalkyl)phenols
Wu, Bo,Gao, Xiang,Chen, Mu-Wang,Zhou, Yong-Gui
supporting information, p. 981 - 984 (2016/02/18)
A concise synthesis of 2-(2-hydroxyphenyl)acetonitriles has been developed through reaction of trimethylsilyl cyanide and the o-quinone methides in situ generated from 2-(1-tosylalkyl)phenols under basic conditions. In addition, 2-(2-hydroxyphenyl)acetonitriles could be conveniently transformed to benzofuranones.
A mild method for generation of o-quinone methides under basic conditions. the facile synthesis of trans-2,3-dihydrobenzofurans
Chen, Mu-Wang,Cao, Liang-Liang,Ye, Zhi-Shi,Jiang, Guo-Fang,Zhou, Yong-Gui
, p. 1660 - 1662 (2013/03/14)
A novel and efficient method for the generation of o-quinone methide intermediates was developed from the readily available 2-tosylalkylphenols under the mild basic conditions, and their reactions with sulfur ylides were investigated for the stereoselective synthesis of trans-2,3-dihydrobenzofurans. The Royal Society of Chemistry 2013.
