142406-11-9

Upstream product

• 590-92-1 3-Bromopropionic acid 
• 59429-73-1 2-chloro-5-methoxybenzenethiol 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 
• 953045-33-5 bis(2-chloro-5-methoxyphenyl)disulfide 
• 2401-24-3 2-chloro-5-methoxyaniline 
• 2732-80-1 2-bromo-1-chloro-4-methoxybenzene 
• 107-96-0 3-mercaptopropionic acid 

Relevant academic research and scientific papers

LIPOXYGENASE INHIBITORS

Various embodiments of the present disclosure are directed to compounds having Formula (I), Formula (IA), Formula (IB), Formula (IC), Formula (ID), Formula (IE), and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases, and/or treating associated diseases, such as Alzheimer's disease. In some embodiments, the compounds may be administered to a patient as part of a pharmaceutical formulation.

Furan Derivatives. Part 13. Synthesis of Thiopyranobenzofuran

Thiopyranobenzofuran 9 possessing benzofuran and methylenethiopyran structures in the molecule was synthesized starting from 1-chloro-4-methoxy-2-nitrobenzene 11.Some reactions (formylation, protonation and catalytic hydrogenation) on 9 were examined.The 2-position of 9 was highly reactive toward electrophilic reagents and the furan ring was readily reduced by catalytic hydrogenation with palladium-charcoal.Thiopyranobenzofuran 9 has both properties of methylenethiopyran and benzofuran.