142409-72-1

Upstream product

• 14316-61-1 phenoxyacetic anhydride 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 701-99-5 Phenoxyacetyl chloride 
• 50-89-5 thymidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 142409-74-3 5'-O-(4,4'-Dimethoxytrityl)-4--thiothymidine 
• 136743-13-0 5'-O-(4,4'-Dimethoxytrityl)-4-(S-p-nitrophenyl)-thiothymidine 
• 749254-20-4 C₇₈H₈₆N₄O₁₆Si 
• 142409-76-5 Phenoxy-acetic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-[5-methyl-4-(4-nitro-phenylsulfanyl)-2-oxo-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl ester 

Relevant academic research and scientific papers

Mispair-aligned N3T-alkyl-N3T interstrand cross-linked DNA: Synthesis and characterization of duplexes with interstrand cross-links of variable lengths

Therapeutic bifunctional alkylating agents generate interstrand cross-links in duplex DNA. As part of our continuing studies on DNA duplexes that contain alkyl interstrand cross-links, we have synthesized a cross-link that bridges the N3 positi

Straightforward Preparation and Use in Oligodeoxynucleotide Synthesis of 5'-O-(4,4'-Dimethoxytrityl)-4-Thiothymidine

The title compound was prepared in four steps and 62percent yield from thymidine.After incorporation into synthetic oligodeoxynucleotides, the S-(2-cyanoethyl) group was removed by treatment with DBU in CH3CN to give products containing 4-thiothymidine residues.