1426099-71-9Relevant articles and documents
Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors
Gampe, Christian M.,Tsukamoto, Hirokazu,Doud, Emma H.,Walker, Suzanne,Kahne, Daniel
supporting information, p. 3776 - 3779 (2013/04/23)
New antibiotic drugs need to be identified to address rapidly developing resistance of bacterial pathogens to common antibiotics. The natural antibiotic moenomycin A is the prototype for compounds that bind to bacterial peptidoglycan glycosyltransferases
CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS
-
Paragraph 00176, (2013/10/22)
The present invention provides methods of synthesizing moenomycin analogs of Formula (I). The present invention also provides compositions comprising a compound of Formula (I) and kits for synthesizing compounds of Formula (I).