1427064-68-3

Upstream product

• 67-56-1 methanol 
• 1364678-33-0 5-(4-chloro-3-fluorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid 
• 137504-86-0 3-fluoro-4-chlorophenylboronic acid 
• 1211586-75-2 5-bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid 

Downstream Products

• 1427064-19-4 5-(4-chloro-3-fluorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid hydrazide 

Relevant academic research and scientific papers

3-PYRIDINE CARBOXYLIC ACID HYDRAZIDES

The present invention relates to compounds of formula I, wherein R1 to R5 are defined in the description and claims, and to pharmaceutically acceptable salts thereof. The present invention relates also to the manufacture of said compounds, pharmaceutical compositions containing them and methods for the treatment and/or prophylaxis of diseases which can be treated with HDL-cholesterol raising agents, such as dyslipidemia, atherosclerosis and cardiovascular diseases.

3-PYRIDINE CARBOXYLIC ACID HYDRAZIDES AS HDL-CHOLESTEROL RAISING AGENTS

The present invention relates to compounds of the formula wherein R1 to R5 are defined in the description and claims, and to pharmaceutically acceptable salts thereof, their manufacture, pharmaceutical compositions containing them and their use as medicaments for the treatment and/or prophylaxis of diseases which can be treated with HDL-cholesterol raising agents, such as particularly dyslipidemia, atherosclerosis and cardiovascular diseases