14316-14-4

Basic information

• Product Name: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide;N-(2-Hydroxyethyl)-4-toluenesulfonaMide
• CAS NO: 14316-14-4
• Molecular Formula: C₉H₁₃NO₃S
• Molecular Weight: 215.26942
• Product Categories: Aromatics;Sulfur & Selenium Compounds
• Mol File: 14316-14-4.mol
• Article Data: 54

Chemical Properties

• Melting Point: 55-57°C
• Boiling Point: 380.2 °C at 760 mmHg
• Flash Point: 183.8 °C
• Appearance: /
• Density: 1.263 g/cm³
• Vapor Pressure: 1.85E-06mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide(14316-14-4)
• EPA Substance Registry System: N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide(14316-14-4)

Safety Data

• Hazardous Substances Data: 14316-14-4(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide (cas# 14316-14-4) is a compound useful in organic synthesis.

InChI:InChI=1/C9H13NO3S/c1-8-2-4-9(5-3-8)14(12,13)10-6-7-11/h2-5,10-11H,6-7H2,1H3

Upstream product

• 141-43-5 ethanolamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 107-09-5 2-bromoethylamine 
• 104-15-4 toluene-4-sulfonic acid 
• 603-35-0 triphenylphosphine 
• 51010-88-9 methyl (2E,4E)-6-bromo-2,4-hexadienoate 
• 202974-92-3 N-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-benzenesulfonamide 
• 2002-24-6 2-amino-ethanol hydrochloride 
• 98-09-9 benzenesulfonyl chloride 
• 57483-27-9 N-(2-oxoethyl)-4-methylbenzenesulfonamide 
• 1219601-57-6 1-(p-tolylsulfonyl)triazole 
• 110-63-4 Butane-1,4-diol 
• 2232-08-8 N-tosylimidazole 
• 142-26-7 2-acetylaminoethanol 

Downstream Products

• 64819-94-9 3,9-di(p-toluenesulfonyl)-6-oxa-3,9-diazaundecane-1,11-diamine 
• 76980-45-5 4,7,13,16,22,25-hexa(p-toluenesulfonyl)-1,10,19-trioxa-4,7,13,16,22,25-hexaazacycloheptaeicosane 
• 76980-40-0 N,N',3,9-tetra(p-toluenesulfonyl)-6-oxa-3,9-diazaundecane-1,11-diamine 
• 76980-39-7 3,9-di(p-toluenesulfonyl)-1,11-di(p-toluenesulfonyloxy)-6-oxa-3,9-diazaundecane 
• 1119121-89-9 N-(2-hydroxyethyl)-4-methyl-N-(3-methylbut-2-en-1-yl)-benzenesulfonamide 
• 1579963-99-7 (2E,4E)-methyl 6-(N-(2-((tert-butyldimethylsilyl)oxy)ethyl)-4-methylphenyl-sulfonamido)hexa-2,4-dienoate 
• 1579963-97-5 (2E,4E)-methyl 6-(N-(2-hydroxyethyl)-4-methylphenylsulfonamido)hexa-2,4-dienoate 
• 1579963-67-9 (2E,4E)-methyl 6-(4-methyl-N-(2-oxoethyl)phenylsulfonamido)hexa-2,4-dienoate 
• 1579963-68-0 (E)-methyl 4-(4-oxo-1-tosylpyrrolidin-3-yl)but-2-enoate 
• 1006726-13-1 N-(2-benzoyloxyethyl)-p-toluenesulfonamide 
• 1006726-12-0 N-(2-pivaloyloxyethyl)-p-toluenesulfonamide 
• 173602-05-6 3-propanal dimethyl acetal 
• 202974-92-3 N-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methyl-benzenesulfonamide 
• 142639-41-6 3,9,12,18-Tetra(toluene-p-sulfonyl)-6,15-dioxa-3,9,12,18-tetraazaicosane-1,20-diol 

Relevant articles and documents

Synthesis and crystal structures of multifunctional tosylates as basis for star-shaped poly(2-ethyl-2-oxazoline)s

The synthesis of well-defined polymer architectures is of major importance for the development of complex functional materials. In this contribution, we discuss the synthesis of a range of multifunctional star-shaped tosylates as potential initiators for the living cationic ring-opening polymerization (CROP) of 2-oxazolines resulting in star-shaped polymers. The synthesis of the tosylates was performed by esterification of the corresponding alcohols with tosyl chloride. Recrystallization of these tosylate compounds afforded single crystals, and the X-ray crystal structures of di-, tetra-and hexa-tosylates are reported. The use of tetra-and hexatosylates, based on (di)pentaerythritol as initiators for the CROP of 2-ethyl-2-oxazoline, resulted in very slow initiation and illdefined polymers, which is most likely caused by steric hindrance in these initiators. As a consequence, a porphyrin-cored tetratosylate initiator was prepared, which yielded a well-defined star-shaped poly(2-ethyl-2-oxazoline) by CROP as demonstrated by SEC with RI, UV and diode-array detectors, as well as by 1H NMR spectroscopy.

Catalyst-Free Visible-Light-Mediated Iodoamination of Olefins and Synthetic Applications

Herein we report a catalyst- and metal-free visible-light-mediated protocol enabling the iodoamination of miscellaneous olefins. This protocol is characterized by high yields under environmentally benign reaction conditions utilizing commercially available substrates and a green and biodegradable solvent. Furthermore, the protocol allows for late-stage functionalization of bioactive molecules and can be scaled to gram quantities of product, which offers manifold possibilities for further transformations, including morpholine, piperidine, pyrrolidine, and aziridine synthesis.

Enantio- and Regioselective Palladium(II)-Catalyzed Dioxygenation of (Aza-)Alkenols

An oxidative Pd-catalyzed intra-intermolecular dioxygenation of (aza-)alkenols has been reported, with total regioselectivity. To study the stereoselectivity, different chiral ligands as well as different hypervalent-iodine compounds have been compared. I