1435-53-6

Usage

Chemical Properties

clear colorless liquid

InChI:InChI=1/C7H4F3NO2S/c8-7(9,10)4-1-2-6(14)5(3-4)11(12)13/h1-3,14H

Upstream product

• 462-06-6 fluorobenzene 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 7726-95-6 bromine 
• 146328-85-0 5-bromo-2-fluoro-benzoic acid 
• 1493-27-2 ortho-nitrofluorobenzene 
• 2924-09-6 5-bromo-2-fluoroaniline 

Downstream Products

• 183065-73-8 3,5-dibromo-2-fluorobenzoic acid 
• 425379-21-1 5'-bromo-6,2'-difluorobiphenyl-2-carbonitrile 
• 850792-76-6 3-[4-(5-bromo-2-fluoro-phenoxy)-2-methyl-phenyl]propionic acid methyl ester 
• 850792-74-4 3-[4-(3-bromo-4-fluoro-phenoxy)-2-methyl-phenyl]propionic acid methyl ester 
• 112204-57-6 dihydroxy-(5-bromo-2-fluorophenyl)-borane 
• 131077-90-2 Methyl 1-(2,4-dibromophenyl)-2-methylimidazole-4-carboxylate 
• 889858-08-6 t-butyl 4-bromo-2-fluorobenzoate 
• 1065607-12-6 3-(2,4-dibromophenoxy)pyridin-2-amine 
• 345635-35-0 (2,4-dibromo-phenyl)-methyl sulfide 
• 1147334-61-9 ethyl 3-(3-bromo-4-fluorophenyl)acrylate 
• 1220329-26-9 (3aR,5R,7aS)-5-(benzyloxymethyl)-7a-(5-bromo-2-fluorophenyl)-1,3,3a,4,5,7-hexahydropyrano[3,4-c]isoxazole 
• 1258647-42-5 2,4-di(2-pyridinyl)fluorobenzene 
• 1379803-47-0 2,4-dibromo-1-(3,5-dimethoxyphenoxy)benzene 
• 1379803-53-8 5-(2,4-dibromophenoxy)benzene-1,3-diol 

Relevant academic research and scientific papers

1,3-dibromo-4-fluorobenzene preparation method

The invention discloses an industrial preparation method of 1,3-dibromo-4-fluorobenzene. The industrial preparation method of 1,3-dibromo-4-fluorobenzene comprises the steps that o-fluoronitrobenzeneserves as an initial raw material, and 1,3-dibromo-4-fluorobenzene is synthesized through bromine applying, reduction and diazotization-Sandmeyer three step reactions. The obtained 1,3-dibromo-4-fluorobenzene is yellow oily liquid, the purity is 97.5%, the raw material conversion rates of all steps each reach 100%, and the total recovery of the whole process reaches 52.7%.

PROCESS FOR THE PREPARATION OF ORGANIC BROMIDES

The present invention provides a process for the preparation of organic bromides, by a radical bromodecarboxylation of carboxylic acids with a bromoisocyanurate.

Preparation process of fluorine substituted aromatic compound

A preparation process of a fluorine substituted aromatic compound comprising reacting an alkali metal or alkali earth metal salt of an aromatic compound having a hydroxy group with an organic fluorinating agent is disclosed. As a representative fluorinating agent, a bis-dialkylamino-difluoromethane compound, for example, 2,2′-difluoro-1,3-dimethylimidazolidine, is exemplified. According to the process, an industrially useful fluorinated aromatic compound, for example, a fluorobenzene, a fluorine substituted benzophenone, a fluorine substituted diarylsulfone can be prepared with ease in economy without specific equipment.

PHOTOCHEMICAL BROMINATION OF ARENES. 2. FLUOROBENZENE DERIVATIVES (1)

Photochemically induced reaction of fluorobenzene and a range of polyfluorobenzenes, both in an excess of the arene and with fluorotrichloromethane as solvent, gave isolable adducts only with fluorobenzene, the isomeric difluorobenzenes, and in very small yield with 1,3,5-trifluorobenzene.These adducts were identified by combustion analysis, mass spectrometry, and n.m.r. techniques (1H, 13C, 19F).In every case, the expected substitution products accompanied these adducts, and in the more fully fluorinated benzene derivatives substitution was the only process observed.Fluorotrichloromethane encouraged the formation of adducts, but the concurrent formation of substantial amounts of substitution products suggested that adducts are not the necessary precursors of the substitution products, in contrast with other systems.