143583-65-7

Basic information

• Product Name: 2,5-Pyrrolidinedione, 1-(2-acetylphenyl)-
• CAS NO: 143583-65-7
• Molecular Formula: C12H11NO3
• Molecular Weight: 217.224
• Mol File: 143583-65-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,5-Pyrrolidinedione, 1-(2-acetylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Pyrrolidinedione, 1-(2-acetylphenyl)-(143583-65-7)
• EPA Substance Registry System: 2,5-Pyrrolidinedione, 1-(2-acetylphenyl)-(143583-65-7)

Safety Data

• Hazardous Substances Data: 143583-65-7(Hazardous Substances Data)

Upstream product

• 123-56-8 Succinimide 
• 2142-69-0 2-bromophenyl methyl ketone 
• 108-30-5 succinic acid anhydride 
• 551-93-9 2-aminoacetophenone 

Downstream Products

• 144876-39-1 1-[2-(2-Bromo-acetyl)-phenyl]-pyrrolidine-2,5-dione 

Relevant articles and documents

A new route to quinolone and indole skeletones via ketone- and ester-imide cyclodehydration reactions

Ketone-imide cyclodehydration reactions of aromatic succinimide and phthalimide (7, 8) have afforded quinolone acids (11, 12). Further transformation of the acids provided the corresponding esters (13, 14) and vinylogous urethanes (9, 10). Similarly, ester-imide cyclodehydration reactions of aromatic imide esters (19, 20) have afforded indole acids (23, 24).

Synthesis and spectroscopic studies of some novel quinoline derivatives

An intramolecular Wittig reaction of some substituted aminoacetophenones was used for the synthesis of novel quinoline derivatives. In addition, the base induced cyclization of the aminoacetophenones was investigated. The IR and NMR spectra of the quinoline derivatives are reported.