14394-91-3

Basic information

• Product Name: 2H-Benzimidazol-2-one,1-acetyl-1,3-dihydro-(9CI)
• Synonyms: 2H-Benzimidazol-2-one,1-acetyl-1,3-dihydro-(9CI);1-(2-hydroxy-1H-benzo[d]imidazol-1-yl)ethanone
• CAS NO: 14394-91-3
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.18
• Product Categories: BENZIMIDAZOLE
• Mol File: 14394-91-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H-Benzimidazol-2-one,1-acetyl-1,3-dihydro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Benzimidazol-2-one,1-acetyl-1,3-dihydro-(9CI)(14394-91-3)
• EPA Substance Registry System: 2H-Benzimidazol-2-one,1-acetyl-1,3-dihydro-(9CI)(14394-91-3)

Safety Data

• Hazardous Substances Data: 14394-91-3(Hazardous Substances Data)

Usage

General Description

2H-Benzimidazol-2-one,1-acetyl-1,3-dihydro-(9CI) is a chemical compound with the molecular formula C10H10N2O2. It is a derivative of benzimidazole and has a cyclic structure consisting of two fused rings. 2H-Benzimidazol-2-one,1-acetyl-1,3-dihydro-(9CI) is also known as 1-acetyl-1,3-dihydro-2H-1,3-benzodiazole-2-one and is used in pharmaceutical research and development, particularly in the study of benzimidazole derivatives as potential drug candidates. Its molecular structure and properties make it a promising candidate for use in the treatment of various diseases such as cancer, malaria, and microbial infections. Additionally, it has potential applications in the field of organic synthesis and catalysis due to its unique properties.

Upstream product

• 108-24-7 acetic anhydride 
• 111008-23-2 (Z)?4?(2?oxopropylidene)?4,5?dihydro?1H?benzo[b][1,4]diazepin?2(3H)?one 
• 95-54-5 1,2-diamino-benzene 
• 615-16-7 1,3-dihydro-2H-benzimidazol-2-one 
• 75-36-5 acetyl chloride 
• 552-32-9 o-nitroacetanilide 
• 2735-73-1 1,3-diacetyl-1,3-dihydro-benzoimidazol-2-one 
• 100-46-9 benzylamine 
• 100142-54-9 1-acetyl-3-(prop-1-en-2-yl)-1H-benzo[d]imidazol-2(3H)-one 
• 51-17-2 benzoimidazole 
• 546-67-8 lead(IV) tetraacetate 

Downstream Products

• 615-16-7 1,3-dihydro-2H-benzimidazol-2-one 
• 3054-47-5 N⁵-((R)-3-(acetylthio)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine 

Relevant articles and documents

Unexpected synthesis of novel 2-pyrone derivatives: crystal structures, Hirshfeld surface analysis and computational studies

Here we report synthesis of three new compounds namely, 1-acetyl-1H-benzimidazolo-2(3H)-one (I), N-(5-acetyl-6-methyl-2-oxo-2H-pyran-4-yl)-N-(2-acetamidophenyl)acetamide (II) and N-(2-acetamidophenyl)-N-2-oxo-2H-pyran-4-yl)acetamide (III) have been synthe

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Selenium-Catalyzed Carbonylative Synthesis of 2-Benzimidazolones from 2-Nitroanilines with TFBen as the CO Source

A selenium-catalyzed carbonylative reaction for the synthesis of 2-benzimidazolones from 2-nitroanilines has been developed. In this strategy, to avoid the usage of toxic CO gas, TFBen (benzene-1,3,5-triyl triformate) was used as a solid and stable CO precursor, and a variety of desired 2-benzimidazolones were produced in moderate to excellent yields.

1,3-Dihydro-1,3-diacetyl-2H-benzimidazol-2-one: A new versatile and selective acetylating agent

1,3-Dihydro-1,3-diacetyl-2H-benzimidazol-2-one (4, DABI) was proven to be a versatile and selective acetylating agent for amines. Selectivity and reactivity are not only superior than those of other known acetylating agents, but also products could be easily separated with excellent yield.