1440429-92-4Relevant academic research and scientific papers
A facile method for the synthesis of dihydroquinoline-Azide from the Lewis acid-catalyzed reaction of alkylidenecyclopropanes with TMSN3
Chen, Mintao,Wei, Yin,Shi, Min
, p. 9990 - 9993 (2019)
A facile synthetic method for the formation of dihydroquinoline-Azide from alkylidenecyclopropanes and TMSN3 under the catalysis of a Lewis acid has been developed, and a number of azide-containing compounds can be instantly accessed in moderate to good yields. A click reaction with these azido compounds was also realized along with a mechanistic investigation.
Palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes with O2: a facile protocol to selectively synthesize 2- and 3-vinylindoles
Cao, Bo,Simaan, Marwan,Marek, Ilan,Wei, Yin,Shi, Min
, p. 216 - 219 (2016/12/27)
A novel palladium-catalyzed oxidative cyclization of aniline-tethered alkylidenecyclopropanes using molecular oxygen as the terminal oxidant through β-carbon elimination of aminopalladation intermediates is disclosed. The reaction opens up an effective way to obtain a series of 2- and 3-vinylindoles which are important synthetic intermediates in many natural indole derivatives.
Palladium-catalyzed cascade cyclization of allylamine-tethered alkylidenecyclopropanes: Facile access to iodine/difluoromethylene- and perfluoroalkyl-containing 1-benzazepine scaffolds
Yu, Liu-Zhu,Zhu, Zi-Zhong,Hu, Xu-Bo,Tang, Xiang-Ying,Shi, Min
supporting information, p. 6581 - 6584 (2016/06/01)
The unprecedented palladium-catalyzed cascade cyclization of allylamine-tethered alkylidenecyclopropanes with an ethyl difluoroiodoacetate or perfluoroalkylated reagent is developed, providing facile access to a variety of synthetically and medicinally valuable iodine/difluoromethylene- and perfluoroalkyl-containing 1-benzazepine frameworks. These reactions exhibited good yields and functional group tolerance via a radical mechanism.
Copper(I)-Catalyzed Intramolecular Trifluoromethylation of Methylenecyclopropanes
Zhu, Zi-Zhong,Chen, Kai,Yu, Liu-Zhu,Tang, Xiang-Ying,Shi, Min
supporting information, p. 5994 - 5997 (2016/01/09)
Copper(I)-catalyzed intramolecular trifluoromethylation of methylenecyclopropanes has been developed to produce a variety of CF3-substituted dihydronaphthalenes in moderate to good yields, relying on the construction of C(sp2)-CFsub
Thermal induced intramolecular [2 + 2] cycloaddition of allene-ACPs
Chen, Kai,Sun, Run,Xu, Qin,Wei, Yin,Shi, Min
supporting information, p. 3949 - 3953 (2013/07/05)
A facile synthetic method for preparation of bicyclo[4.2.0] nitrogen heterocycles has been developed via a thermal induced intramolecular [2 + 2] cycloaddition reaction of allene-ACPs. The DFT calculations indicate that this intramolecular cycloaddition proceeds in a concerted manner and a strained small ring is essential. The Royal Society of Chemistry 2013.
