1445721-28-7Relevant articles and documents
Development of an imidazole salt catalytic system for the preparation of bis(indolyl) methanes and bis(naphthyl)methane
Wang, Xu,Aldrich, Courtney C.
, (2019/05/04)
Imidazolium salts are shown to catalyze the rapid room temperature reaction of indoles or naphthol with aldehydes to provide bis(indolyl)methanes or bis(naphthol)methane in excellent yields and the reaction proceeds optimally in dichloromethane with no base additives. The reaction exhibits a broad substrate tolerance and occurs through nucleophilic activation of the indoles and naphthols through a cation–π interaction.