14464-30-3

Basic information

• Product Name: CAPRYLIC ACID N-SUCCINIMIDYL ESTER
• Synonyms: Caprylic acid-N-hydroxysuccinimide ester;N-(Octanoyloxy)succinimide, N-Succinimidyl caprylate, N-Succinimidyl octanoate;Eliglustat intermediate 6;2,5-dioxopyrrolidin-1-yl octanoate;1-(Octanoyloxy)-2,5-pyrrolidinedione;Octanoic acid 2,5-dioxo-pyrrolidin-1-yl ester
• CAS NO: 14464-30-3
• Molecular Formula: C₁₂H₁₉NO₄
• Molecular Weight: 241.28356
• Mol File: 14464-30-3.mol

Chemical Properties

• Melting Point: 61-63 °C
• Boiling Point: 333.2±25.0 °C(Predicted)
• Appearance: /
• Density: 1.13±0.1 g/cm3(Predicted)
• Storage Temp.: −20°C
• CAS DataBase Reference: CAPRYLIC ACID N-SUCCINIMIDYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CAPRYLIC ACID N-SUCCINIMIDYL ESTER(14464-30-3)
• EPA Substance Registry System: CAPRYLIC ACID N-SUCCINIMIDYL ESTER(14464-30-3)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 14464-30-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
CAPRYLIC ACID N-SUCCINIMIDYL ESTER is used as an intermediate for the synthesis of various pharmaceutical compounds. Its ability to react with different functional groups makes it a valuable building block in the development of new drugs.
Used in Chemical Synthesis:
In the chemical industry, CAPRYLIC ACID N-SUCCINIMIDYL ESTER is used as a reagent for the preparation of various organic compounds. Its high reactivity and specificity in reactions contribute to the synthesis of complex molecules with desired properties.
Used in Eliglustat Preparation:
CAPRYLIC ACID N-SUCCINIMIDYL ESTER is used as a key intermediate in the preparation of eliglustat and its tartrate form. Eliglustat is a drug used for the treatment of Gaucher disease, a genetic disorder that affects the body's ability to break down a certain type of fat.

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 111-64-8 n-octanoic acid chloride 
• 124-07-2 Octanoic acid 
• 124-13-0 Octanal 
• 111-87-5 octanol 
• 74124-79-1 di(succinimido) carbonate 

Downstream Products

• 950491-35-7 N-(4-formylbenzyl)octanamide 
• 1354638-42-8 α-(4-octanamidomethyl)phenyl-N-(2-hydroxymethyl-1,3-dihydroxy-2-propyl)nitrone 
• 1354638-47-3 C₂₀H₃₁N₂O₅ 
• 133849-27-1 N^α-octanoyl-L-valine 
• 491833-29-5 (1R,2R)-octanoic acid [2-(2',3'-dihydro-benzo[1,4]dioxin-6'-yl)-2-hydroxy-1-pyrrolidin-1-ylmethyl-ethyl]-amide 
• 52854-12-3 N⁶-octanoyladenine 
• 1080673-14-8 C₂₂H₃₆O₃Si 
• 1039560-17-2 C₂₂H₃₆O₃Si 
• 188048-68-2 Capr-Ser(Bzl)-Asp(OBzl)-Ala-Arg(NO₂)-OMe 
• 82816-57-7 benzyl 2,6-dideoxy-6-(eicosanoylamino)-3-O--2-(octanoylamino)-5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside 
• 81148-69-8 benzyl 2-(benzyloxycarbonylamino)-2,6-dideoxy-3-O--6-(octanoylamino)-5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside 
• 81148-70-1 benzyl 2,6-dideoxy-2,6-di(octanoylamino)-3-O--5-O-(tetrahydropyran-2-yl)-β-D-glucofuranoside 

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