14474-22-7Relevant articles and documents
Development of a photoswitchable antagonist of NMDA receptors
Hartrampf, Felix W.W.,Barber, David M.,Gottschling, Kevin,Leippe, Philipp,Hollmann, Michael,Trauner, Dirk
, p. 4905 - 4912 (2017/07/27)
N-methyl–Daspartate receptors (NMDARs) are vital for neurological processes such as learning, memory, and synaptic plasticity. As such, small molecules that modulate their function are of interest in the study of numerous neurological diseases. We have synthesized a small library of photoswitches that modulate NMDAR function. The most efficient photoswitch to date is based on a known ligand of the glycine binding site and shows significant subtype selectivity.
Bis(azobenzene)-based photoswitchable, prochiral, Cα- tetrasubstituted α-amino acids for nanomaterials applications
Fatas, Paola,Longo, Edoardo,Rastrelli, Federico,Crisma, Marco,Toniolo, Claudio,Jimenez, Ana I.,Cativiela, Carlos,Moretto, Alessandro
supporting information; experimental part, p. 12606 - 12611 (2011/12/21)
Light-driven chirality: Sequential light-driven isomerization of prochiral, bis(azobenzene)-containing amino acids results in the formation of chiral entities that have been characterized by different techniques. Metal nanoparticles conjugated with these amino acids retain the photoswitching properties and show conformation-dependent magnetic susceptibility that can be reversibly controlled by irradiation (see figure).
