14496-34-5

Basic information

• Product Name: N,N-dimethyl-2-furfurylamine
• Synonyms: N,N-dimethyl-2-furfurylamine;2-DIMETHYLAMINOMETHYLFURAN;N,N-Dimethyl-2-furanmethanamine;N,N-Dimethylfuran-2-methanamine;Einecs 238-506-0;2-FuranMethanaMine,N,N-diMethyl-
• CAS NO: 14496-34-5
• Molecular Formula: C₇H₁₁NO
• Molecular Weight: 125.16834
• EINECS: 238-506-0
• Mol File: 14496-34-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 127.7°Cat760mmHg
• Flash Point: 31°C
• Appearance: /
• Density: 0.971g/cm³
• Vapor Pressure: 11mmHg at 25°C
• Refractive Index: 1.477
• CAS DataBase Reference: N,N-dimethyl-2-furfurylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-2-furfurylamine(14496-34-5)
• EPA Substance Registry System: N,N-dimethyl-2-furfurylamine(14496-34-5)

Safety Data

• Hazardous Substances Data: 14496-34-5(Hazardous Substances Data)

Usage

General Description

N,N-dimethyl-2-furfurylamine is a chemical compound with the formula C8H11NO. It is a tertiary amine and furan derivative, and it consists of a furan ring with a dimethylamine substituent and a furfuryl group. N,N-dimethyl-2-furfurylamine has various industrial uses, including as a corrosion inhibitor and as a reagent in organic synthesis. It is also used as a flavor and fragrance ingredient in the food and beverage industry. N,N-dimethyl-2-furfurylamine has potential health hazards, including skin and eye irritation, and should be handled with care in a well-ventilated area.

InChI:InChI=1/C7H11NO/c1-8(2)6-7-4-3-5-9-7/h3-5H,6H2,1-2H3

Upstream product

• 151-50-8 potassium cyanide 
• 541-64-0 Furmethide 
• 98-01-1 furfural 
• 124-40-3 dimethyl amine 
• 58-86-6 D-xylose 
• 127-19-5 N,N-dimethyl acetamide 
• 68-12-2 N,N-dimethyl-formamide 
• 50-00-0 formaldehyd 
• 617-89-0 furan-2-ylmethanamine 
• 14002-21-2 dimethylaminomethanol 
• 110-00-9 furan 
• 30354-18-8 N,N-dimethyl(methylene)ammonium chloride 

Downstream Products

• 30727-09-4 dimethyl-(tetrahydrofuran-2-yl-methyl)amine 
• 37642-90-3 Dimethyl-ethyl--ammoniumiodid 
• 102-05-6 N-methyldibenzylamine 
• 81404-55-9 N-methyl,N-benzyl furfurylamine 
• 75-50-3 trimethylamine 
• 623-17-6 furfurylacetate 
• 66357-35-5 Ranitidine 

Relevant articles and documents

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Method for preparing tertiary amine organic compound from photocatalytically decomposing substituted formamide

The invention discloses a method for preparing a tertiary amine compound from aldehyde and substituted formamide under the action of a photocatalyst. The method is characterized in that the reaction can be performed only by illumination under the conditions of no hydrogen and no reducing agent. The method is suitable for various aldehydes including aromatic aldehydes, fatty aldehydes and the like,has the characteristics of few byproducts and high product yield, does not need to use hydrogen in the reaction, avoids the use of noble metal hydrogenation catalysts, and has obvious technical and economic effects and application prospects.

Simplified preparation of a graphene-co-shelled Ni/NiO@C nano-catalyst and its application in theN-dimethylation synthesis of amines under mild conditions

The development of Earth-abundant, reusable and non-toxic heterogeneous catalysts to be applied in the pharmaceutical industry for bio-active relevant compound synthesis remains an important goal of general chemical research.N-methylated compounds, as one of the most essential bioactive compounds, have been widely used in the fine and bulk chemical industries for the production of high-value chemicals. Herein, an environmentally friendly and simplified method for the preparation of graphene encapsulated Ni/NiO nanoalloy catalysts (Ni/NiO@C) was developed for the first time, for the highly selective synthesis ofN-methylated compounds using various functional amines and aldehydes under easy to handle, and industrially applicable conditions. A large number of primary and secondary amines (more than 70 examples) could be converted to the correspondingN,N-dimethylamines with the participation of different functional aldehydes, with an average yield of over 95%. A gram-scale synthesis also demonstrated a similar yield when compared with the benchmark test. In addition, it was further proved that the catalyst could easily be recycled because of its intrinsic magnetism and reused up to 10 times without losing its activity and selectivity. Also, for the first time, the tandem synthesis ofN,N-dimethylamine products in a one-pot process, using only a single earth-abundant metal catalyst, whose activity and selectivity were more than 99% and 94%, respectively, for all tested substrates, was developed. Overall, the advantages of this newly developed method include operational simplicity, high stability, easy recyclability, cost-effectiveness of the catalyst, and good functional group compatibility for the synthesis ofN-methylation products as well as the industrially applicable tandem synthesis process.

Method for preparing tertiary amine organic compounds by using substituted formamide

The invention discloses a method for preparing tertiary amine organic compounds by using substituted formamide. According to the method, aldehyde is used as a reaction substrate, substituted formamideis used as a solvent, reducing agent and aminating agent, a metal oxide/hydroxide is added as a catalyst, and a small amount of water is added as an auxiliary agent; heating and stirring are carriedout so as to form corresponding tertiary amine compounds; and a reaction can be conducted only through heating without hydrogen and a reducing agent. The method of the invention is applicable to various aldehydes including aromatic aldehydes, fatty aldehydes, etc., and has the characteristics of few by-products and high product yield; and hydrogen is not used in the reaction, and the use of a noble metal hydrogenation catalyst is avoided, so the method has remarkable technical and economic effects and application prospects.