1451002-44-0Relevant academic research and scientific papers
Total synthesis of a novel isoquinolinone alkaloid marinamide and its methyl ester
Zhang, Shuguang,Feng, Chengliang,Cai, Jin,Chen, Junqing,Ji, Min
, p. 291 - 293 (2013/07/27)
A naturally occurring isoquinolinone alkaloid marinamide and its methyl ester were synthesised from phthalic anhydride over eight steps in 46% and 52% overall yield. The key intermediate methyl 2-(1-benzyl-1H-pyrrole-2-carbonyl) benzoate was synthesised from the acid chloride of mono methyl phthalate and 1-benzyl-1H-pyrrole catalysed by Zinc oxide under solvent-free conditions at room temperature.
