1451067-59-6

Basic information

• Product Name: 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-((2-((2-oxo-2H-furo[3,2-g]chromen-9-yl)oxy)ethyl)amino)pentanenitrile
• Synonyms: 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-((2-((2-oxo-2H-furo[3,2-g]chromen-9-yl)oxy)ethyl)amino)pentanenitrile
• CAS NO: 1451067-59-6
• Molecular Weight: 504.583
• Mol File: 1451067-59-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-((2-((2-oxo-2H-furo[3,2-g]chromen-9-yl)oxy)ethyl)amino)pentanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-((2-((2-oxo-2H-furo[3,2-g]chromen-9-yl)oxy)ethyl)amino)pentanenitrile(1451067-59-6)
• EPA Substance Registry System: 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-((2-((2-oxo-2H-furo[3,2-g]chromen-9-yl)oxy)ethyl)amino)pentanenitrile(1451067-59-6)

Safety Data

• Hazardous Substances Data: 1451067-59-6(Hazardous Substances Data)

Upstream product

• 298-81-7 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one 
• 27487-83-8 2-(3,4-dimethoxyphenyl)-2-isopropyl-2-(3-chloropropyl)acetonitrile 
• 20850-49-1 2-(3,4-dimethoxyphenyl)-3-methylbutyronitrile 
• 58042-53-8 9-(2-bromoethoxy)-7H-furo[3,2-g]chromen-7-one 
• 27487-66-7 D 620 
• 2009-24-7 8-hydroxypsoralen 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 

Relevant articles and documents

Design, synthesis and evaluation of 9-hydroxy-7H-furo [3,2-g]chromen-7-one derivatives as new potential vasodilatory agents

Two new 9-hydroxy-7H-furo[3,2-g]chromen-7-one derivatives were designed, synthesized and evaluated for their in vitro vasodilatory activity. The structures of two compounds were elucidated by infrared, 1H NMR, and mass spectral data. The invitro pharmacological evaluation indicated that both of them possessed well vasodilatory activity compared with imperatorin. The molecule docking also showed two target compounds docked well with L-calcium channel (PDB code: 3G43). The result suggested that they would be potential vasodilatory agents for hypertension.