146137-37-3

Upstream product

• 100606-34-6 (2E)-3-(4-methoxy-2-methylphenyl)-2-propenoic acid 
• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 
• 2935-35-5 (S)-2-phenylglycine 
• 111292-75-2 (4S)-3-((2E)-2-butenoyl)-4-phenyl-1,3-oxazolidin-2-one 
• 148706-30-3 2-methyl-4-methoxyphenylmagnesium bromide 
• 75-16-1 methylmagnesium bromide 
• 146137-32-8 (4S)-4-phenyl-3-<3-(4'-methoxy-2'-methylphenyl)-2(E)-propenoyl>-2-oxazolidinone 
• 27060-75-9 4-bromo-3-methylanisole 

Relevant academic research and scientific papers

Diastereospecific tandem Michael-like addition/electrophilic bromination: A one-pot tandem asymmetric synthesis of precursors of unusual amino acids

A systematic series of key intermediates of unusual β-methyl-amino acids have been synthesized by using a modified Evans auxiliary in an asymmetric Michael-like reaction followed by direct bromination in a one-pot reaction.