100606-34-6

Basic information

• Product Name: (E)-3-(4-methoxy-2-methylphenyl)acrylic acid
• Synonyms: (E)-3-(4-methoxy-2-methylphenyl)acrylic acid
• CAS NO: 100606-34-6
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21118
• Mol File: 100606-34-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-3-(4-methoxy-2-methylphenyl)acrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-methoxy-2-methylphenyl)acrylic acid(100606-34-6)
• EPA Substance Registry System: (E)-3-(4-methoxy-2-methylphenyl)acrylic acid(100606-34-6)

Safety Data

• Hazardous Substances Data: 100606-34-6(Hazardous Substances Data)

Usage

General Description

(2E)-3-(4-methoxy-2-methylphenyl)-2-propenoic acid, also known as p-methoxycinnamic acid, is a chemical compound with a molecular formula of C11H12O3. It is a derivative of cinnamic acid and belongs to the class of phenylpropanoids. (2E)-3-(4-methoxy-2-methylphenyl)-2-propenoic acid is often found in various plant species and is known for its antioxidant and anti-inflammatory properties. It has been studied for its potential therapeutic effects in conditions such as cardiovascular disease, diabetes, and cancer. Additionally, p-methoxycinnamic acid is used in the production of various pharmaceuticals, food additives, and as a flavoring agent in the food and cosmetic industries.

Upstream product

• 100-84-5 1-methoxy-3-methyl-benzene 
• 27060-75-9 4-bromo-3-methylanisole 
• 174810-40-3 (E)-3-(4-methoxy-2-methylphenyl)acrylic acid tert-butyl ester 
• 141-82-2 malonic acid 
• 52289-54-0 4-methoxysalicylaldehyde 

Downstream Products

• 174810-39-0 2-chloro-3-hydroxy-5-(4-methoxy-2-methylphenyl)penta-2,4-dienoic acid methyl ester 
• 174810-38-9 5-(4-methoxy-2-methylphenyl)-3-oxopent-4-enoic acid methyl ester 
• 100606-37-9 ethyl (E)-3-(4-methoxy-2-methylphenyl)-2-propenoate 
• 146137-37-3 (3(3R),4S)-4-phenyl-3-<3-(4'-methoxy-2'-methylphenyl)butanoyl>-2-oxazolidinone 
• 86786-22-3 3-(4-methoxy-2-methylcyclohexa-1,4-dienyl)propionic acid 
• 146137-32-8 (4S)-4-phenyl-3-<3-(4'-methoxy-2'-methylphenyl)-2(E)-propenoyl>-2-oxazolidinone 

Relevant articles and documents

ANTI-HIV COMPOUNDS

This invention provides, among other things, tetrahydroisoquinolines useful for treating viral infections, pharmaceutical formulations containing such compounds, as well as methods of inhibiting the replication of a virus, such as HIV, or treating a disease, such as AIDS.

A concise synthesis of the naphthoic acid component of neocarzinostatin chromophore featuring a new photocyclization reaction

A 6-step synthesis of the naphthoic acid component of the natural antitumor agent neocarzinostatin chromophore is described. The synthetic route employs 4-bromo-3-methylanisole as the starting material, proceeds in 31-37% yield for the 6 steps, and featur

Organoiron Complexes in Organic Synthesis. Part 27. Synthesis and Reactivity of Tricarbonyliron Derivatives of 1,2-Disubstituted 4-Alkoxycyclohexadienylium Cations

The synthesis, and reactions with stable enolate nucleophiles, of 1,2-disubstituted 4-alkoxycyclohexadienylium(tricarbonyl)iron complexes (3a), (3b), (3c), and (3d) is described.Only the 1,2-dimethyl-4-isopropoxycyclohexadienylium complex (3b) was found to react with nucleophiles with sufficiently high regioselectivity to allow a useful method of preparation of 3,4,4-trisubstituted cyclohexenones.