1462-96-0

Usage

Uses

Used in Perfumery and Cosmetics Industry:
1-Ethylcyclopentanol is used as a fragrance ingredient for its refreshing scent, contributing to the creation of perfumes, soaps, and cosmetics. Its minty and floral notes enhance the sensory experience of these products, making them more appealing to consumers.
Used in the Plastics and Resins Industry:
As a solvent, 1-Ethylcyclopentanol plays a crucial role in the manufacturing process of plastics, resins, and other related materials. Its solvent properties facilitate the production of these materials by aiding in the dissolution and mixing processes.
Used in Pharmaceutical Manufacturing:
1-Ethylcyclopentanol is utilized as a solvent in the pharmaceutical industry, where it assists in the formulation and production of various medications. Its ability to dissolve a range of substances makes it a valuable component in the development of pharmaceutical formulations.
Used as an Intermediate in Organic Synthesis:
1-Ethylcyclopentanol serves as an intermediate in the synthesis of other organic compounds. Its chemical structure allows it to be a building block for more complex organic molecules, which can be used in a wide array of applications across different industries.
While 1-Ethylcyclopentanol is generally considered to have low toxicity, it is important to note that prolonged exposure to high concentrations may result in irritation to the skin, eyes, and respiratory system. Proper handling and safety measures should be taken to mitigate any potential adverse effects.

InChI:InChI=1/C7H14O/c1-2-6-4-3-5-7(6)8/h6-8H,2-5H2,1H3

Upstream product

• 10467-10-4 ethylmagnesium iodide 
• 120-92-3 cyclopentanone 
• 925-90-6 ethylmagnesium bromide 
• 811-49-4 ethyllithium 
• 17356-19-3 1-ethynylcyclopentanol 
• 14660-52-7 ethyl 5-bromovalerate 
• 97-94-9 triethyl borane 
• 38118-79-5 1-cyclopentylethan-1-amine 
• 7782-77-6 cis-nitrous acid 
• 75-03-6 ethyl iodide 
• 2015-57-8 1-benzylcyclopentanol 
• 2386-64-3 ethylmagnesium chloride 
• 19873-00-8 1-Chlor-1-ethylcyclopentan 

Downstream Products

• 2146-38-5 1-ethylcyclopentene 
• 2146-37-4 ethylidenecyclopentane 
• 3896-31-9 1-Ethyl-1-acetamido-cyclopentan 
• 92104-68-2 1-Ethyl-1-phenyl-cyclopentan 
• 2565-39-1 hept-6-en-3-one 
• 31849-01-1 δ-chlorobutyl ethyl ketone 
• 2955-59-1 3,12-tetradecanedione 
• 106-35-4 heptan-3-one 
• 120-92-3 cyclopentanone 
• 3742-80-1 1-ethylcyclopentyl acetate 
• 431-03-8 dimethylglyoxal 
• 3301-90-4 6-ethyl-tetrahydro-2H-pyran-2-one 
• 16747-50-5 1-ethyl-1-methyl-cyclopentane 
• 1403684-88-7 C₁₄H₁₉F₂O₇S^(1-)*C₁₈H₁₅S⁽¹⁺⁾ 

Relevant academic research and scientific papers

ETHERS AND ESTERS OF 1-SUBSTITUTED CYCLOALKANOLS FOR USE AS AROMA CHEMICALS

The present invention relates to the use of an ether or an ester of a 1 -substituted cycloalkanol or of mixtures of two or more ethers or esters of 1 -substituted cycloalkanols or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof as aroma chemicals; to the use thereof for modifying the scent character of a fragranced composition; to an aroma chemical composition containing an ether or an ester of a 1 -substituted cycloalkanol or of mixtures of two or more ethers or esters of 1 -substituted cycloalkanols or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof; and to a method of preparing a fragranced composition or for modifying the scent character of a fragranced composition. The invention further relates to specific ethers or esters of 1 -substituted cycloalkanols.

Diester acid protection structure monomer and preparation method thereof

The invention relates to the field of optical materials and in particular to a diester acid protection structure monomer and a preparation method thereof. The diester acid protection structure monomeris used as a raw material of a photoresist required in integrated circuit manufacturing. Due to a diester long side chain, the photoresist has a better film-forming property; due to the fact that small-size and high-acid-sensitivity groups hung outside can improve the deprotection reaction efficiency in the photoetching process, the quality of a photoetched product is improved; and in addition, the diester acid protection structure monomer prepared through the process method has high yield and purity, and the performance of the photoresist is further guaranteed.

Carbon Dioxide as a Directing Group for C-H Functionalization Reactions Involving Lewis Basic Amines, Alcohols, Thiols, and Phosphines for the Synthesis of Compounds

Methods of synthesizing compounds using CO2 as a directing group for C—H functionalization, and compounds made thereby, are described.

Transaminase Triggered Aza-Michael Approach for the Enantioselective Synthesis of Piperidine Scaffolds

The expanding “toolbox” of biocatalysts opens new opportunities to redesign synthetic strategies to target molecules by incorporating a key enzymatic step into the synthesis. Herein, we describe a general biocatalytic approach for the enantioselective preparation of 2,6-disubstituted piperidines starting from easily accessible pro-chiral ketoenones. The strategy represents a new biocatalytic disconnection, which relies on an ω-TA-mediated aza-Michael reaction. Significantly, we show that the reversible enzymatic process can power the shuttling of amine functionality across a molecular framework, providing access to the desired aza-Michael products.

Photolysis of 1-alkylcycloalkanols in the presence of (diacetoxyiodo) benzene and I2. Intramolecular selectivity in the β-scission reactions of the intermediate 1-alkylcycloalkoxyl radicals

The C-C β-scission reactions of 1-alkylcycloalkoxyl radicals, generated photochemically by visible light irradiation of CH2Cl 2 solutions containing the parent 1-alkylcycloalkanols, (diacetoxy)-iodobenzene (DIB), and I2, have been investigated through the analysis of the reaction products. The 1-alkylcycloalkoxyl radicals undergo competition between ring opening and C-alkyl bond cleavage as a function of ring size and of the nature of the alkyl substituent. With the 1-propylcycloheptoxyl, 1-propylcyclooctoxyl, and 1-phenylcyclooctoxyl radicals, formation of products deriving from an intramolecular 1,5-hydrogen atom abstraction reaction from the cycloalkane ring has also been observed. The results are discussed in terms of release of ring strain associated to ring opening, stability of the alkyl radical formed by C-alkyl cleavage, and with cycloheptoxyl and cyclooctoxyl radicals, also in terms of the possibility of achieving a favorable geometry for intramolecular hydrogen atom abstraction.

2,3,5-TRISUBSTITUTED PYRIDINES AS INHIBITORS OF CYCLOOXYGENASE-2

The invention encompasses the novel compound of Formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula (I).

Stereoselective synthesis of δ-lactones from 5-oxoalkanals via one-pot sequential acetalization, tishchenko reaction, and lactonization by cooperative catalysis of samarium ion and mercaptan

By the synergistic catalysis of samarium ion and mercaptan, a series of 5-oxoalkanals was converted to (substituted) δ-lactones in efficient and stereoselective manners. This one-pot procedure comprises a sequence of acetalization, Tishchenko reaction and lactonization. The deliberative use of mercaptan, by comparison with alcohol, is advantageous to facilitate the catalytic cycle. The reaction mechanism and stereochemistry are proposed and supported by some experimental evidence. Such samarium ion/mercaptan cocatalyzed reactions show the feature of remote control, which is applicable to the asymmetric synthesis of optically active δ-lactones. This study also demonstrates the synthesis of two insect pheromones, (2S,5R)-2-methylhexanolide and (R)-hexadecanolide, as examples of a new protocol for asymmetric reduction of long-chain aliphatic ketones.

Electrochemical alkyl transfer reactions of trialkylborane to carbonyl compounds by use of copper sacrificial anode

Alkyl groups in trialkylboranes were successfully transferred to carbonyl compounds in the presence of the platinum cathode and copper anode by electrochemical method. The new, mild electrochemical alkyl transfer reaction produced various substituted alcohols in good yields.

Alkylation-annulation of halo esters with organometallic reagent/SmI2 couple leading to cycloalkanols: A facile cyclopropanol synthesis from a 3-halo ester

Transformation of a 3-halo ester to cyclopropanols has been accomplished in excellent yields under mild conditions employing a coupled reagent of samarium(II) diiodide with organometallic reagents. 5- and 6-Halo esters were also transformed into cyclopentanols and cyclohexanols, respectively, in low to moderate yields. The reaction with a 4-halo ester gave 2,2-disubstituted tetrahydrofuran as a major product that resulted from double alkylation followed by cyclization; a substituted cyclobutanol was formed in poor yield.