146578-13-4

Basic information

• Product Name: Phosphorous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-ylmethyl ester dimethyl ester
• CAS NO: 146578-13-4
• Molecular Weight: 561.65
• Mol File: 146578-13-4.mol

Chemical Properties

• CAS DataBase Reference: Phosphorous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-ylmethyl ester dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphorous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-ylmethyl ester dimethyl ester(146578-13-4)
• EPA Substance Registry System: Phosphorous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-ylmethyl ester dimethyl ester(146578-13-4)

Safety Data

• Hazardous Substances Data: 146578-13-4(Hazardous Substances Data)

Upstream product

• 122194-07-4 dimethyl N,N-diisopropylphosphoramidite 
• 51549-40-7 6-N-benzoyl-3'-O-(tert-butyldimethylsilyl)-2'-deoxyadenosine 
• 64325-78-6 N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 
• 4546-72-9 N₆-benzoyl-2'-deoxyadenosine 
• 146578-12-3 5’-O-(4,4’dimethoxytrityl)-N6-(benzoyl)-3’-O-tert-butyldimethylsilyldeoxyadenosine 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 146578-16-7 C₅₈H₆₈N₁₀O₁₃P₂ 
• 146578-15-6 [(2S,3S,5R)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-phosphoramidic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester methyl ester 
• 146578-14-5 C₅₅H₆₅N₈O₁₂PSi 

Relevant articles and documents

Synthesis and Selective Cleavage of an Oligodeoxynucleotide Containing a Bridged Non-Chiral Internucleotide 3'-Phosphoramidate Linkage

A self complementary oligodeoxynucleotide dodecamer containing an achiral bridged 3'-phosphoramidate linkage 3'-NH-P-O-5' has been prepared using the solid phase phosphoramidate procedure.Cleavage of the P-N bond can be accomplished selectively by mild acidolysis.