146578-16-7Relevant articles and documents
Synthesis and Selective Cleavage of an Oligodeoxynucleotide Containing a Bridged Non-Chiral Internucleotide 3'-Phosphoramidate Linkage
Mag, Matthias,Schmidt, Rainer,Engels, Joachim W.
, p. 7319 - 7323 (2007/10/02)
A self complementary oligodeoxynucleotide dodecamer containing an achiral bridged 3'-phosphoramidate linkage 3'-NH-P-O-5' has been prepared using the solid phase phosphoramidate procedure.Cleavage of the P-N bond can be accomplished selectively by mild acidolysis.