14688-32-5

Basic information

• Product Name: 4-benzyl-3,5-diphenylisoxazole
• Synonyms: 4-benzyl-3,5-diphenylisoxazole
• CAS NO: 14688-32-5
• Molecular Weight: 311.383
• Mol File: 14688-32-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-benzyl-3,5-diphenylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyl-3,5-diphenylisoxazole(14688-32-5)
• EPA Substance Registry System: 4-benzyl-3,5-diphenylisoxazole(14688-32-5)

Safety Data

• Hazardous Substances Data: 14688-32-5(Hazardous Substances Data)

Upstream product

• 72705-83-0 4-benzyl-3-phenylisoxazol-5(4H)-one 
• 1076-59-1 3-phenyl-4H-isoxazol-5-one 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 98-80-6 phenylboronic acid 
• 26060-56-0 (1-phenylethylidene)(benzoyloxy)amine 
• 14688-28-9 (3,5-diphenylisoxazol-4-yl)(phenyl)methanone 
• 28918-09-4 2-benzyl-1,3-diphenyl-propane-1,3-dione 

Relevant articles and documents

Suzuki-Miyaura cross-coupling of 3,4-disubstituted 5-bromoisoxazoles: An efficient access to trisubstituted isoxazoles

The Suzuki-Miyaura cross-coupling of 3,4-disubstituted 5-bromoisoxazoles 1 at the C5 position has successfully proceeded in the presence of Pd2(dba)3 and P(t-Bu)3·HBF4 catalysts to give the corresponding trisubstituted isoxazoles 3 in good to high yields while suppressing the formation of ketone 4 as a byproduct. The use of bulky phosphine ligand P(t-Bu)3·HBF4 is essential for the current transformation, and the formation of ketone 4, which was a major product in the previous report, was able to be suppressed under the current conditions.