1469-74-5

Usage

Uses

Used in Coatings and Inks Industry:
3,4'-DINITROBENZOPHENONE is used as a photosensitizer for the production of UV-curable coatings and inks. Its ability to absorb light and initiate the curing process under UV radiation makes it an essential component in the formulation of these products, ensuring rapid and efficient curing.
Used in Dyes and Pigments Industry:
3,4'-DINITROBENZOPHENONE is used as an intermediate in the synthesis of dyes and pigments. Its chemical properties allow for the creation of a wide range of colorants, which are then utilized in various applications such as textiles, plastics, and printing inks.
Used in Pharmaceutical Industry:
3,4'-DINITROBENZOPHENONE is used as an intermediate in the preparation of pharmaceuticals. Its unique chemical structure contributes to the development of new drugs and active pharmaceutical ingredients, enhancing the therapeutic potential of various medications.
Used in Perfumery Industry:
3,4'-DINITROBENZOPHENONE is used in the preparation of perfumes, where it serves as a key intermediate in the synthesis of various fragrance compounds. Its ability to create complex and long-lasting scents makes it a valuable component in the perfume industry.
Safety Considerations:

Upstream product

• 3002-33-3 4-(3'-nitrobenzyl)-nitrobenzene 
• 119-61-9 benzophenone 
• 1144-74-7 4-nitrobenzophenone 
• 201230-82-2 carbon monoxide 
• 586-36-7 3-nitrophenyldiazonium tetrafluoroborate 
• 91734-78-0 p-nitrophenyltriethylstannane 
• 77133-16-5 (2R,3R)-2-(4-Nitro-phenyl)-3-(3-nitro-phenyl)-oxirane 
• 91-01-0 1,1-Diphenylmethanol 
• 7697-37-2 nitric acid 
• 7664-93-9 sulfuric acid 
• 2243-80-3 3-nitrobenzophenone 
• 157195-20-5 (3-nitro-phenyl)-(4-nitro-phenyl)-acetic acid 
• 64-19-7 acetic acid 
• 408539-86-6 1,1,1-trichloro-2-(3-nitro-phenyl)-2-(4-nitro-phenyl)-ethane 

Downstream Products

• 1370037-16-3 diethyl (hydroxy)(3-nitrophenyl)(4-nitrophenyl)methylphosphonate 
• 19430-83-2 3,4'-diaminodiphenylmethane 
• 611-81-4 (3-hydroxyphenyl)(4-hydroxyphenyl)methanone 
• 83699-50-7 3,4'-bis-acetylamino-benzophenone 

Relevant academic research and scientific papers

Guanidinium-based derivatives: Searching for new kinase inhibitors

Considering the structural similarities between the kinase inhibitor sorafenib and 4,4′-bis-guanidinium derivatives previously prepared by Rozas and co., which display interesting cytotoxicity in cancer cells, we have studied whether this activity could result from kinase inhibition. Five new families have been prepared consisting of unsubstituted and aryl-substituted 3,4′-bis-guanidiniums, 3,4′-bis-2-aminoimidazolinium and 3-acetamide-4′-(4-chloro-3-trifluoromethylphenyl)guanidinium derivatives. Cytotoxicity (measuring the IC50 values) and apoptosis studies in human HL-60 promyelocytic leukemia cells were carried out for these compounds. Additionally, their potential inhibitory effect was explored on a panel of kinases known to be involved in apoptotic pathways. The previously prepared cytotoxic 4,4′-bis-guanidiniums did not inhibit any of these kinases; however, some of the novel 3,4′-substituted derivatives showed a high percentage inhibition of RAF-1/MEK-1, for which the potential mode of binding was evaluated by docking studies. The interesting antitumour properties showed by these compounds open up new exciting lines of investigation for kinase inhibitors as anticancer agents and also highlights the relevance of the guanidinium moiety for protein kinase inhibitors chemical design.

Polymer electrolyte and process for producing the same

A polymer electrolyte having, in a main chain, a structural unit represented by the following formula (1):-[Ar1-(SO2-N-(X+)-SO2-Ar2)m-SO2-N-(X+)-SO2-Ar1-O]- wherein Ar1 and Ar2 independently represent a divalent aromatic groups, m represents an integer of 0 to 3, and X+ represents an ion selected from hydrogen ion, an alkali metal ion and ammonium ion, which is excellent in proton conductivity, thermal resistance and strength. The polymer electrolyte is soluble in solvents and has excellent film forming property and recycling efficiency.

Ozone-mediated Nitration of Aromatic Ketones and Related Compounds with Nitrogen Dioxide

Alkyl aryl ketones react smoothly with nitrogen dioxide at low temperatures in the presence of ozone to give ortho- and meta-nitro derivatives as the principal products, the former usually being predominant (ortho:meta = 1.1-3.8:1.0).No attack was observed on the alkyl side chains.

Reaction of Diazonium Salts with Transition Metals. Part 13. Palladium-catalyzed Carbonylative Coupling of Arenediazonium Salts with Organotin Reagents to give Aromatic Ketones

Palladium-catalyzed reactions of arenediazonium salts (ArN2X; Ar=Y-Ph, Y=H, 2-, 3-, 4-Me, 2-Ph, 2-, 3-MeO, 2-, 3-, 4-Cl, 4-Br, 4-I, 2-, 3-, and 4-NO2, X=BF4 and PF6) with carbon monoxide and organostannanes (R4Sn, R=Me, Et, and Ph; RSnMe3, R=Ph, 2-, 3-, 4-MeC6H4, and 4-ClC6H4; RSnEt3, R=4-NO2C6H4; RSnBu3, R=Ph) gave aromatic ketones (ArCOR) in good yields (40-95percent) at room temperature.