1469-95-0Relevant articles and documents
Oxidation of olefins by palladium(II): Part 17. An asymmetric chlorohydrin synthesis catalyzed by a bimetallic palladium(II) complex
El-Qisairi, Arab,Henry, Patrick M.
, p. 50 - 60 (2007/10/03)
Previous studies showed that oxidation of α-olefins with monometallic catalysts containing chiral diphosphines and diamines gave chlorohydrins with poor to good enantioselectivites (28-82% ee). The present studies demonstrate that bimetallic catalysts containing a β-triketone and bridging chiral diphosphine and diamines are excellent catalysts for this reaction giving enantioselectivites considerably higher than the monometallic catalysts. Enantioselectivities were more than 50% for most olefins tested. The highest optical purities were 94% ee for propene and 93% ee for allylphenyl ether. A useful feature of this asymmetric synthesis is the fact it is a net air oxidation.
Polycarbonylmethyl Derivatives: Reactions of 2-(3-Methyl-5-isoxazolyl)-1-phenylethanone
Eiden, Fritz,Patzelt, Gertrud
, p. 242 - 251 (2007/10/02)
Starting with the compound 11, the isoxazole derivatives 22a and 27a are synthesized.These compounds are transformed to the substituted isoxazoles 23, 25 and 28.Catalytic hydrogenation of the isoxazol derivatives 11, 15 and 23 gives the 1,3,5-tricarbonyl
α,α' Dianions of Aliphatic Ketones and the 1,3,5-Trianion of 2,4-Pentanedione: Strongly Nucleophilic Carbonyl Synthons
Hubbard, James S.,Harris, Thomas M.
, p. 2110 - 2112 (2007/10/02)
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