147490-72-0Relevant academic research and scientific papers
Novel Solid-phase Synthesis of Branched Oligoribonucleotides, including a Substrate for the RNA Debranching Enzyme
Sproat, Brian S.,Beijer, Barbro,Groetli, Morten,Ryder, Ursula,Morand, Kenneth L.,Lamond, Angus I.
, p. 419 - 432 (2007/10/02)
An effective new route for synthesizing branched oligoribionucleotides in the solid phase in the 5' to 3' direction has been developed.This required the synthesis of reversed monomers, viz. protected nucleoside 5'-phosphoramidites bearing 2'-O-Fpmp and 3'
Use of the 1-(2-Fluorophenyl)-4-methoxypiperidin-4-yl (Fpmp) Protecting Group in the Solid-Phase Synthesis of Oligo- and Poly-ribonucleotides
Rao, M. Vaman,Reese, Colin B.,Schehlmann, Volker,Yu, Pak Sang
, p. 43 - 56 (2007/10/02)
An approach to the solid-phase synthesis of oligo- and poly-ribonucleotides is described.The synthetic strategy involves the use of building blocks in which two acid-labile groups, 1-(2-fluorophenyl)-4-methoxypiperidin-4-yl (Fpmp) and 9-phenylxanthen-9-yl
