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Usage

Uses

Used in Pharmaceutical Industry:
3-Mesylphenol is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its chemical properties make it a valuable component in the creation of medicinal compounds.
Used in Dye Industry:
In the dye industry, 3-Mesylphenol is utilized as an intermediate in the production of dyes, capitalizing on its chemical structure to yield a range of colorants for various applications.
Used in Organic Synthesis:
3-Mesylphenol is employed as a reagent in organic synthesis, facilitating a variety of chemical reactions that are essential in the preparation of organic compounds.
Used in Water Treatment:
As a corrosion inhibitor in water treatment, 3-Mesylphenol helps to prevent the deterioration of metal surfaces in contact with water, thereby extending the life of water systems and equipment.
Used in Medicinal Chemistry Research:
3-Mesylphenol is used as a subject of study in medicinal chemistry for its potential as an anti-inflammatory and anti-cancer agent, indicating its possible role in the development of therapeutic agents.
It is crucial to handle 3-Mesylphenol with care due to its corrosive and irritating nature, ensuring safety in its application across different fields.

Upstream product

• 43032-67-3 1-methanesulfonyl-3-methoxy-benzene 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 34896-80-5 1-bromo-3-methanesulphonylbenzene 
• 80213-28-1 3-methylsulfonylaniline hydrochloride 
• 2976-32-1 1-methanesulfonyl-3-nitro-benzene 
• 2388-74-1 1-methoxy-3-methylsulfanyl-benzene 
• 35216-39-8 3-(methylsulfonyl)aniline 

Downstream Products

• 103262-86-8 3-(methylsulfonyl)phenyl acetate 
• 1167571-99-4 C₁₄H₁₃BrO₃S 
• 802905-29-9 S-[3-(methylsulfonyl)phenyl]carbamothioic acid dimethyl ester 

Relevant academic research and scientific papers

Radical-anion coupling through reagent design: hydroxylation of aryl halides

The design and development of an oxime-based hydroxylation reagent, which can chemoselectively convert aryl halides (X = F, Cl, Br, I) into phenols under operationally simple, transition-metal-free conditions is described. Key to the success of this approach was the identification of a reducing oxime anion which can interact and couple with open-shell aryl radicals. Experimental and computational studies support the proposed radical-nucleophilic substitution chain mechanism.

MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF DISORDERS RELATED THERETO

The present invention relates to compounds of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the beta-3 adrenergic receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of a beta-3 adrenergic receptor-mediated disorder, such as, heart failure; cardiac performance in heart failure; mortality, reinfarction, and/or hospitalization in connection with heart failure; acute heart failure; acute decompensated heart failure; congestive heart failure; severe congestive heart failure; organ damage associated with heart failure (e.g., kidney damage or failure, heart valve problems, heart rhythm problems, and/or liver damage); heart failure due to left ventricular dysfunction; heart failure with normal ejection fraction; cardiovascular mortality following myocardial infarction; cardiovascular mortality in patients with left ventricular failure or left ventricular dysfunction; left ventricular failure; left ventricular dysfunction; class II heart failure using the New York Heart Association (NYHA) classification system; class III heart failure using the New York Heart Association (NYHA) classification system; class IV heart failure using the New York Heart Association (NYHA) classification system; LVEF 40% by radionuclide ventriculography; LVEF ≤35% by echocardiography or ventricular contrast angiography; and conditions related thereto.

SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT

Substituted cyclopropyl compounds of formula (I) are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.

Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases

Compounds of the general formula (I): wherein the variables are as defined in the specification are useful for the prophylaxis or treatment of serotonin-related, especially 5-HT2receptor-related, diseases in human beings or animals, particularly diseases related to the 5-HT2creceptor, especially diseases such as eating disorders, memory disorders, schizophrenia, mood disorders, anxiety disorders, pain, sexual dysfunctionions, and urinary disorders.