14763-61-2

Basic information

• Product Name: 3-Mesylphenol
• Synonyms: 3-(Methylsulfonyl)phenol;3-Mesylphenol;3-Methanesulfonyl-phenol
• CAS NO: 14763-61-2
• Molecular Formula: C₇H₈O₃S
• Molecular Weight: 172.20162
• Mol File: 14763-61-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: pK1:9.33 (25°C)
• CAS DataBase Reference: 3-Mesylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Mesylphenol(14763-61-2)
• EPA Substance Registry System: 3-Mesylphenol(14763-61-2)

Safety Data

• Hazardous Substances Data: 14763-61-2(Hazardous Substances Data)

Usage

General Description

3-Mesylphenol, also known as 3-methylbenzenesulfonic acid, is a chemical compound with the molecular formula C7H8O3S. It is a white to light pink solid that is soluble in water and organic solvents. 3-Mesylphenol is commonly used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also used as a reagent in organic synthesis and as a corrosion inhibitor in water treatment. Additionally, 3-Mesylphenol has been studied for its potential use as an anti-inflammatory and anti-cancer agent, making it of interest in the field of medicinal chemistry. However, it is important to handle 3-Mesylphenol with care as it is a corrosive and irritating compound.

Upstream product

• 34896-80-5 1-bromo-3-methanesulphonylbenzene 
• 80213-28-1 3-methylsulfonylaniline hydrochloride 
• 2976-32-1 1-methanesulfonyl-3-nitro-benzene 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 2388-74-1 1-methoxy-3-methylsulfanyl-benzene 
• 43032-67-3 1-methanesulfonyl-3-methoxy-benzene 
• 35216-39-8 3-(methylsulfonyl)aniline 

Downstream Products

• 103262-86-8 3-(methylsulfonyl)phenyl acetate 
• 106276-57-7 1-benzoyloxy-3-methanesulfonyl-benzene 
• 43032-67-3 1-methanesulfonyl-3-methoxy-benzene 

Relevant articles and documents

Radical-anion coupling through reagent design: hydroxylation of aryl halides

The design and development of an oxime-based hydroxylation reagent, which can chemoselectively convert aryl halides (X = F, Cl, Br, I) into phenols under operationally simple, transition-metal-free conditions is described. Key to the success of this approach was the identification of a reducing oxime anion which can interact and couple with open-shell aryl radicals. Experimental and computational studies support the proposed radical-nucleophilic substitution chain mechanism.

SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT

Substituted cyclopropyl compounds of formula (I) are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.