14770-93-5

Basic information

• Product Name: Benzofuran, 5,6-dimethyl-2,3-diphenyl-
• CAS NO: 14770-93-5
• Molecular Formula: C22H18O
• Molecular Weight: 298.384
• Mol File: 14770-93-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzofuran, 5,6-dimethyl-2,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran, 5,6-dimethyl-2,3-diphenyl-(14770-93-5)
• EPA Substance Registry System: Benzofuran, 5,6-dimethyl-2,3-diphenyl-(14770-93-5)

Safety Data

• Hazardous Substances Data: 14770-93-5(Hazardous Substances Data)

Upstream product

• 95-65-8 3,4-Dimethylphenol 
• 501-65-5 diphenyl acetylene 
• 98-88-4 benzoyl chloride 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 451-40-1 phenyl benzyl ketone 
• 24932-48-7 1,2-dibromo-4,5-dimethylbenzene 

Relevant articles and documents

Benzofuran synthesis via copper-mediated oxidative annulation of phenols and unactivated internal alkynes

The first example of copper-mediated oxidative annulation of phenols and unactivated internal alkynes to afford benzofuran derivatives was reported. Various phenols and unactivated internal alkynes were successfully employed. Mechanistic studies disclosed a new strategy on annulations of alkynes with phenols through reversible electrophilic carbocupration of phenol followed by alkyne insertion and cyclization.

Palladium-catalyzed cross-coupling of benzyl ketones and α,β- unsaturated carbonyl and phenolic compounds with o-dibromobenzenes to produce cyclic products

A number of carbonyl and phenolic compounds efficiently couple with o- dibromobenzenes in the presence of a palladium catalyst and a base to give the corresponding oxygen-containing heterocycles or carbocyclic compounds. Thus, from the reactions of benzyl phenyl ketones, 1-naphthols, and α,β- unsaturated aldehydes and ketones, benzofuran, benzopyran, benzocyclobutane, and indene derivatives, respectively, are produced selectively via the successive formation of C-C and C-O bonds or of two C-C bonds.