1481-41-0

Basic information

• Product Name: CHLORODIMETHYL-3,3,3-TRIFLUOROPROPYLSILANE
• Synonyms: chlorodimethyl(3,3,3-trifluoropropyl)-silan;DIMETHYL(3,3,3-TRIFLUOROPROPYL)CHLOROSILANE;CHLORODIMETHYL-3,3,3-TRIFLUOROPROPYLSILANE;(3,3,3-TRIFLUOROPROPYL)CHLORODIMETHYLSILANE;(3,3,3-TRIFLUOROPROPYL)DIMETHYLCHLOROSILANE;Trifluoropropyldimethylchlorosilane;(3,3,3-Trifluoropropyl)chlorodimethylsilane 97%;(3,3,3-Trifluoropropyl)chlorodimethylsilane97%
• CAS NO: 1481-41-0
• Molecular Formula: C₅H₁₀ClF₃Si
• Molecular Weight: 190.67
• EINECS: 216-039-3
• Mol File: 1481-41-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 118 °C(lit.)
• Flash Point: 29.9 °C
• Appearance: Clear colorless/Liquid
• Density: 1.117 g/mL at 20 °C(lit.)
• Refractive Index: n20/D 1.378(lit.)
• Sensitive: Moisture Sensitive
• BRN: 1741726
• CAS DataBase Reference: CHLORODIMETHYL-3,3,3-TRIFLUOROPROPYLSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: CHLORODIMETHYL-3,3,3-TRIFLUOROPROPYLSILANE(1481-41-0)
• EPA Substance Registry System: CHLORODIMETHYL-3,3,3-TRIFLUOROPROPYLSILANE(1481-41-0)

Safety Data

• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 26-28-36/37/39-45
• RIDADR: UN 2985 3/PG 2
• WGK Germany: 3
• F: 10-21
• TSCA: Yes
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 1481-41-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H10ClF3Si/c1-10(2,6)4-3-5(7,8)9/h3-4H2,1-2H3

Upstream product

• 592-09-6 3,3,3-trifluoropropyltrichlorosilane 
• 1184-58-3 dimethylaluminum chloride 
• 675-62-7 methyl(3,3,3-trifluoropropyl)dichlorosilane 
• 75-77-4 chloro-trimethyl-silane 
• 650-29-3 Ethoxy-dimethyl-<3,3,3-trifluor-propyl>-silan 
• 917-54-4 methyllithium 
• 1066-35-9 dimethylmonochlorosilane 
• 677-21-4 1,1,1-trifluoropropylene 

Downstream Products

• 39482-87-6 1,3-bis(3,3,3-trifluoropropyl)-1,1,3,3-tetramethyldisilazane 
• 677007-44-2 4-bromo{dimethyl(3,3,3-trifluoropropyl)silyl}benzene 
• 345632-97-5 1,1,2,2-Tetraphenyl-1,2-(dimethyl-3,3,3-trifluoropropylsiloxy)ethane 
• 5906-74-1 (3,3,3-trifluoropropyl)dimethylsilanol 
• 75-77-4 chloro-trimethyl-silane 
• 650-29-3 Ethoxy-dimethyl-<3,3,3-trifluor-propyl>-silan 

Relevant articles and documents

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Steroidal Silicon Side-Chain Analogues as Potential Antifertility Agents

A number of silicon-substituted analogues of ethynylestradiol that exhibit modified and enhanced biological activities have been synthesized.Particularly noteworthy are a group of estradiol analogues that exhibit high antifertility potency and markedly reduced estrogenic activity.The best compounds synthesized are 17α-estradiol (5) and 17α-estradiol (33), which show a separation of antifertility from estrogenic activity in the rat.The results of structure-activity studies indicate a good correlation between the observed biological activities and the calculated van der Waals volumes of the three variable silicon substituents.

CATALYTIC REARRANGEMENT REACTIONS BETWEEN CHLORO- AND ALKOXY-SILANES

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