14850-97-6

Basic information

• Product Name: Benzoic acid, (2E)-(1-phenylethylidene)hydrazide
• CAS NO: 14850-97-6
• Molecular Formula: C15H14N2O
• Molecular Weight: 238.289
• Mol File: 14850-97-6.mol
• Article Data: 33

Chemical Properties

• CAS DataBase Reference: Benzoic acid, (2E)-(1-phenylethylidene)hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, (2E)-(1-phenylethylidene)hydrazide(14850-97-6)
• EPA Substance Registry System: Benzoic acid, (2E)-(1-phenylethylidene)hydrazide(14850-97-6)

Safety Data

• Hazardous Substances Data: 14850-97-6(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 613-94-5 benzoic acid hydrazide 
• 536-74-3 phenylacetylene 
• 93-58-3 benzoic acid methyl ester 
• 65-85-0 benzoic acid 
• 126382-70-5 benzoylacetaldehyde benzoylhydrazone 
• 7654-03-7 N′-(1-phenylethyl)benzohydrazide 
• 41804-90-4 N-Benzoyl-N-trifylhydrazin 
• 585-71-7 (1-bromoethyl)benzne 

Downstream Products

• 17505-70-3 2-acetoxy-5-methyl-2,5-diphenyl-2,5-dihydro-[1,3,4]oxadiazole 
• 85452-67-1 1-benzoyl-3-phenyl-5-(4-tolyl)pyrazole 
• 128722-00-9 Benzoic acid N'-(cyano-methyl-phenyl-methyl)-hydrazide 
• 25445-77-6 4-phenyl-1,2,3-thiadiazole 
• 98-88-4 benzoyl chloride 
• 98-86-2 acetophenone 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 142068-35-7 (R)-(+)-1-phenyl-1-(2-benzoylhydrazino)ethane 
• 142068-32-4 (S)-(-)-1-phenyl-1-(2-benzoylhydrazino)ethane 
• 7654-03-7 N′-(1-phenylethyl)benzohydrazide 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 100-41-4 ethylbenzene 
• 100-47-0 benzonitrile 

Relevant articles and documents

Palladium-Catalyzed Carbonylative Synthesis of 3-Methyleneisoindolin-1-ones from Ketimines with Hexacarbonylmolybdenum(0) as the Carbon Monoxide Source

An interesting procedure for the palladium-catalyzed carbonylative synthesis of 3-methyleneisoindolin-1-ones from ketimines was established. By using Mo(CO)6 (0.3 equiv.) as the solid CO source and through C(sp2)?H bond activation, t

Dinuclear gold(I)-N-heterocyclic carbene complexes: Synthesis, characterization, and catalytic application for hydrohydrazidation of terminal alkynes

Dinuclear gold(I)-N-heterocyclic carbene complexes were developed for the hydrohydrazidation of terminal alkynes. The gold(I)-N-heterocyclic carbene complexes 2a-2b were synthesized in good yields from silver complexes synthesized in situ, which in turn were obtained from the corresponding imidazolium salts with Ag2O in dichloromethane as a solvent. The new air-stable gold(I)-NHC complexes, 2a-2b, were characterized using NMR spectroscopy, elemental analysis, infrared, and mass spectroscopy studies. The gold(I) complex 2a was characterized using X-ray crystallography. Bis-N-heterocyclic carbene–based gold(I) complexes 2a-2b exhibited excellent catalytic activities for hydrohydrazidation of terminal alkynes yielding acylhydrazone derivatives. The working catalytic system can be used in gram-scale synthesis. In addition, the catalytic reaction mechanism of the hydrohydrazidation of terminal alkynes by gold(I)-NHC complex was studied in detail using density functional theory.

Efficient [(NHC)Au(NTf2)]-catalyzed hydrohydrazidation of terminal and internal alkynes

The efficient hydrohydrazidation of terminal (6a–r, 18 examples, 0.1–0.2 mol % [(NHC)Au(NTf2)], T = 60 °C) and internal alkynes (7a–j, 10 examples, 0.2–0.5 mol % [(NHC)Au(NTf2)], T = 60–80 °C) utilizing a complex with a sterically demanding bispentiptycenyl-substituted NHC ligand and the benign reaction solvent anisole, is reported.