148626-66-8

Basic information

• Product Name: hydroxyitraconazole
• CAS NO: 148626-66-8
• Molecular Formula: C35H38Cl2N8O5
• Molecular Weight: 721.63282
• Mol File: 148626-66-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: hydroxyitraconazole(CAS DataBase Reference)
• NIST Chemistry Reference: hydroxyitraconazole(148626-66-8)
• EPA Substance Registry System: hydroxyitraconazole(148626-66-8)

Safety Data

• Hazardous Substances Data: 148626-66-8(Hazardous Substances Data)

Upstream product

• 211627-37-1 2,4-dihydro-2-[(1R,2R)-2-hydroxy-1-methylpropyl]-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one 
• 154003-21-1 ((2S,4S)-2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methyl-benzenesulfonate 
• 184177-81-9 phenyl N-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)carbamate 
• 74853-08-0 1-(4-aminophenyl)-4-(4-hydroxyphenyl)piperazine 
• 172587-60-9 (-)-(2S,cis)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol 
• 170210-46-5 cis-2-bromomethyl-2-(2,4-dichlorophenyl)-4-phenylcarbonyloxymethyl-1,3-dioxolane 
• 2631-72-3 2,4-dichlorophenacyl bromide 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 
• 211627-35-9 2,4-dihydro-2-[(1S,2S)-2-hydroxy-1-methylpropyl]-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one 
• 172587-61-0 cis-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol methanesulfonate (ester) 
• 199797-87-0 2S,4R,2'S,3'R hydroxy itraconazole 
• 74853-07-9 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl ]-phenyl]-3H-1,2,4-triazol-3-one 
• 154003-23-3 (2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-4-tozyloxymethyl-1,3-dioxolane 

Relevant articles and documents

Antifungal water-soluble compound as well as preparation method and application thereof (by machine translation)

The invention provides an antifungal water-soluble compound, a preparation method thereof and application, of the compound as I shown in formula. The compound has good antifungal effect and water solubility, can be used for treating and preventing,configuration optical isomers of the optical isomer SRSS obtained by chiral synthesis. (by machine translation)

Efficient stereoselective synthesis of cis, syn-hydroxyitraconazole isomers

The first stereoselective synthesis of cis, syn-hydroxyitraconazole isomers via a tricomponent coupling strategy is described. The isomers are prepared from two chiral subunits and connected via an achiral linker. A highly stereoselective route to the cis,syn-isomers is presented.