149004-75-1

Upstream product

• 28357-95-1 1-(4-carboxyphenyl)ethylamine 
• 36283-44-0 N-acetyl-1-phenylethylamine 
• 859163-61-4 (R)-4-(1-acetamidoethyl)benzoic acid 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 586-89-0 4-acetyl-benzoic acid 
• 1443-80-7 4-cyanophenyl methyl ketone 

Downstream Products

• 1318865-17-6 trans-(R)-4-(1-aminoethyl)cyclohexanecarboxylic acid methyl ester 
• 1318865-18-7 trans-(R)-4-(1-aminoethyl)cyclohexanecarboxylic acid hydrochloride 
• 1318865-29-0 C₁₉H₂₈FN₃O₃ 
• 1318865-32-5 C₁₉H₂₈FN₃O₃ 
• 129830-38-2 (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide dihydrochloride 
• 671816-04-9 trans-tert-butyl (R)-1-[4-(pyridin-4-ylcarbamoyl)cyclohexyl]ethylcarbamate 
• 671815-99-9 (1R,4r)-4-((R)-1-((tert-butoxycarbonyl)amino)ethyl)cyclohexanecarboxylic acid 

Relevant academic research and scientific papers

A practical synthesis of Rho-Kinase inhibitor Y-27632 and fluoro derivatives and their evaluation in human pluripotent stem cells

A practical synthesis of the Rho-Kinase inhibitor Y-27632 and two new fluoro derivatives was achieved in seven steps and with a good overall yield of 45% starting from commercially available (R)-1-phenylethylamine. Compared to Y-27632 the new fluoro deriv