14949-49-6Relevant articles and documents
Titanocene(II)-promoted cyclization of unsaturated thioacetals
Fujiwara, Tooru,Takeda, Takeshi
, p. 354 - 356 (1999)
The low-valent titanium species-promoted transformation of unsaturated thioacetals to cyclic compounds was studied. The cyclization of thioacetals having an olefin moiety proceeded with the loss of terminal olefin carbon to produce the corresponding five-
Role of the gem-difluoro moiety in the tandem ring-closing metathesis-olefin isomerization: Regioselective preparation of unsaturated lactams
Fustero, Santos,Sanchez-Rosello, Maria,Jimenez, Diego,Sanz-Cervera, Juan F.,Del Pozo, Carlos,Acena, Jose Luis
, p. 2706 - 2714 (2007/10/03)
Careful selection of the metathesis catalyst, solvent, and reaction conditions allows for the efficient and regioselective synthesis of isomeric fluorinated and nonfluorinated lactam derivatives II and III from precursor amides I through a ring-closing me
2,3,4,5-tetrahydro-1-benzoxepins, the use thereof and pharmaceutical products based on these compounds
-
, (2008/06/13)
2,3,4,5-Tetrahydro-1-benzoxepins of the formula I STR1 with R1 equaling, inter alia, H, alkyl, alkoxy, Hal, alkylsulfonyl, arylsulfonyl, R2 equaling H, alkyl, alkoxy, OH, R3 to R6 H or alkyl and X equaling STR2 have excellent efficacy as antihypertensives, as coronary therapeutics, as agents for the treatment of cardiac insufficiency, of disturbances of cerebral and peripheral blood flow or of disturbances of intestinal motility, premature labor, obstructions of the airways or of the urinary tract or of the biliary tract or as spasmolytics.