14949-49-6

Basic information

• Product Name: 2,3-dihydrobenzo[b]oxepine
• Synonyms: 2,3-dihydrobenzo[b]oxepine
• CAS NO: 14949-49-6
• Molecular Formula: C₁₀H₁₀O
• Molecular Weight: 146.1858
• Mol File: 14949-49-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 240.1°Cat760mmHg
• Flash Point: 92.4°C
• Appearance: /
• Density: 1.056g/cm³
• Vapor Pressure: 0.0597mmHg at 25°C
• Refractive Index: 1.552
• CAS DataBase Reference: 2,3-dihydrobenzo[b]oxepine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydrobenzo[b]oxepine(14949-49-6)
• EPA Substance Registry System: 2,3-dihydrobenzo[b]oxepine(14949-49-6)

Safety Data

• Hazardous Substances Data: 14949-49-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 34, p. 207, 1969 DOI: 10.1021/jo00838a045

InChI:InChI=1/C10H10O/c1-2-7-10-9(5-1)6-3-4-8-11-10/h1-3,5-7H,4,8H2

Upstream product

• 6786-30-7 3,4-dihydro-1-benzoxepin-5(2H)-one 
• 20426-87-3 (±)-2,3,4,5-tetrahydro-1-benzoxepin-5-ol 
• 108-95-2 phenol 
• 2364-59-2 γ-phenoxybutyric acid ethyl ester 
• 6303-58-8 4-phenyloxybutanoic acid 
• 18268-10-5 salicylaldehyde diphenyl dithioacetal 
• 3383-05-9 allyl 2-allylphenyl ether 

Downstream Products

• 1421681-67-5 4-[bis(tosyloxy)methyl]-3,4-dihydro-2Hchromene 
• 33313-82-5 (3,4-dihydro-2H-chromen-4-yl)methanol 

Relevant articles and documents

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Careful selection of the metathesis catalyst, solvent, and reaction conditions allows for the efficient and regioselective synthesis of isomeric fluorinated and nonfluorinated lactam derivatives II and III from precursor amides I through a ring-closing me

2,3,4,5-tetrahydro-1-benzoxepins, the use thereof and pharmaceutical products based on these compounds

2,3,4,5-Tetrahydro-1-benzoxepins of the formula I STR1 with R1 equaling, inter alia, H, alkyl, alkoxy, Hal, alkylsulfonyl, arylsulfonyl, R2 equaling H, alkyl, alkoxy, OH, R3 to R6 H or alkyl and X equaling STR2 have excellent efficacy as antihypertensives, as coronary therapeutics, as agents for the treatment of cardiac insufficiency, of disturbances of cerebral and peripheral blood flow or of disturbances of intestinal motility, premature labor, obstructions of the airways or of the urinary tract or of the biliary tract or as spasmolytics.