2364-59-2

Basic information

• Product Name: 4-PHENOXY-N-BUTYRIC ACID ETHYL ESTER
• Synonyms: 4-PHENOXY-N-BUTYRIC ACID ETHYL ESTER;ETHYL 4-PHENOXYBUTYRATE;ETHYL 4-PHENOXY-N-BUTYRATE;4-phenoxybutyric acid ethyl ester;4-PHENOXY-N-BUTYRIC ACID ETHYL ESTER 93+%;4-Phenoxybutanoic acid ethyl ester;ethyl 4-(phenoxy)butanoate
• CAS NO: 2364-59-2
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.25
• Mol File: 2364-59-2.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 173 °C / 25mmHg
• Flash Point: 125.6°C
• Appearance: /
• Density: 1.06
• Vapor Pressure: 0.000704mmHg at 25°C
• Refractive Index: 1.4960 to 1.4990
• CAS DataBase Reference: 4-PHENOXY-N-BUTYRIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PHENOXY-N-BUTYRIC ACID ETHYL ESTER(2364-59-2)
• EPA Substance Registry System: 4-PHENOXY-N-BUTYRIC ACID ETHYL ESTER(2364-59-2)

Safety Data

• Hazardous Substances Data: 2364-59-2(Hazardous Substances Data)

Usage

General Description

4-PHENOXY-N-BUTYRIC ACID ETHYL ESTER is a synthetic chemical compound that falls into the category of esters. It is commonly used as a herbicide and plant growth regulator. When applied to plants, it acts as a growth hormone and can help stimulate root formation and increase flowering. This chemical has low toxicity to mammals but can be harmful if inhaled or ingested. It is important to handle and store 4-PHENOXY-N-BUTYRIC ACID ETHYL ESTER with care and in accordance with safety guidelines to prevent potential harm to humans and the environment.

InChI:InChI=1/C12H16O3/c1-2-14-12(13)9-6-10-15-11-7-4-3-5-8-11/h3-5,7-8H,2,6,9-10H2,1H3

Upstream product

• 100-66-3 methoxybenzene 
• 140-88-5 ethyl acrylate 
• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 1746-13-0 allyl phenyl ether 
• 157245-87-9 4-(4-bromophenoxy)butyric acid ethyl ester 
• 108-95-2 phenol 
• 588-63-6 3-phenoxypropyl bromide 
• 1787-17-3 diethyl 2-phenoxyethyl-propanedioate 
• 881015-10-7 (E)-4-(2-Iodo-phenoxy)-but-2-enoic acid ethyl ester 
• 7647-01-0 hydrogenchloride 
• 6303-58-8 4-phenyloxybutanoic acid 
• 2969-81-5 Ethyl 4-bromobutyrate 
• 3153-36-4 4-chloro-butyric acid ethyl ester 

Downstream Products

• 127283-63-0 3,4-dihydro-7-nitro-1-benzoxepine-5(2H)-one 
• 588-63-6 3-phenoxypropyl bromide 

Relevant articles and documents

Benzoxepine-5-ketone compound as well as preparation method and application thereof

The invention relates to a benzoxazepine-5-ketone compound as well as a preparation method and application thereof. The benzoxazepine-5-ketone compound has a structure as shown in a formula (I) defined in the description. The benzoxazepine-5-ketone compound can block the excessive generation of pro-inflammatory factors in the brain, and provides a feasible alternative treatment strategy for treating AIS.

Chemoselective and Site-Selective Lysine-Directed Lysine Modification Enables Single-Site Labeling of Native Proteins

The necessity for precision labeling of proteins emerged during the efforts to understand and regulate their structure and function. It demands selective attachment of tags such as affinity probes, fluorophores, and potent cytotoxins. Here, we report a method that enables single-site labeling of a high-frequency Lys residue in the native proteins. At first, the enabling reagent forms stabilized imines with multiple solvent-accessible Lys residues chemoselectively. These linchpins create the opportunity to regulate the position of a second Lys-selective electrophile connected by a spacer. Consequently, it enables the irreversible single-site labeling of a Lys residue independent of its place in the reactivity order. The user-friendly protocol involves a series of steps to deconvolute and address chemoselectivity, site-selectivity, and modularity. Also, it delivers ordered immobilization and analytically pure probe-tagged proteins. Besides, the methodology provides access to antibody-drug conjugate (ADC), which exhibits highly selective anti-proliferative activity towards HER-2 expressing SKBR-3 breast cancer cells.

Aldehydes can switch the chemoselectivity of electrophiles in protein labeling

We show that the chemoselectivity of an electrophile in protein labeling can be promiscuous. An aldehyde enables switching of chemoselectivity of an epoxide and a sulfonate ester along with an enhanced rate of reaction. The chemical technology renders single-site installation of diverse probes on a protein and delivers analytically pure tagged proteins.