149873-56-3

Basic information

• Product Name: 3-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one
• Synonyms: 3-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one
• CAS NO: 149873-56-3
• Molecular Weight: 322.794
• Mol File: 149873-56-3.mol

Chemical Properties

• CAS DataBase Reference: 3-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one(149873-56-3)
• EPA Substance Registry System: 3-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one(149873-56-3)

Safety Data

• Hazardous Substances Data: 149873-56-3(Hazardous Substances Data)

Upstream product

• 947-95-5 5-chloro-4-formyl-3-methyl-1-phenyl-1H-pyrazole 
• 98-86-2 acetophenone 
• 100-63-0 phenylhydrazine 
• 89-25-8 edaravone 

Downstream Products

• 1252882-34-0 C₂₂H₂₁ClN₄O 
• 1343477-91-7 3-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-5-phenyl-4,5-dihydroisoxazole 
• 1343477-93-9 C₂₅H₂₁ClN₄ 
• 1262386-48-0 2-amino-3-(4-chlorophenylazo)-5-phenyl-7-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-pyrazolo[1,5-a]pyrimidine 

Relevant articles and documents

Synthesis of 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6-(substituted phenyl)pyrimidin-2-ol analogues as anti-inflammatory and analgesic agents

A series of 16 novel 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6- (substituted-phenyl)pyrimidin-2-ol analogues was synthesized in satisfactory yields after toxicity prediction and drug score studies by Osiris software followed by anti-inflammatory, a

Synthesis and pharmacological evaluation of 5-chloro-3-methyl-1-substituted phenyl-1H-pyrazol-4-yl-1-phenyl pyrimidines and related compounds

Chalcones, (2E)-3-(5-chloro-3-methyl-1-phenyl-1 H-pyrazol-4-yl)-1- phenylprop-2-en-1-ones 1a-b have been prepared from ketone and 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde. These chalcones 1a-b on cyclization with urea, thiourea, hydroxylamine hydrochloride and phenyl hydrazine gave the corresponding oxopyrimidines 2a-b, thiopyrijnidines 5a-b, isoxazolines 3a-b and pyrazolines 4a-b respectively. The structures of all the synthesized compounds were confirmed by spectral data and have been screened for antibacterial, antifungal and analgesic activity.

Synthesis and pharmacological study of 1-acetyl/propyl-3-aryl-5-(5-chloro- 3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-pyrazoline

A series of 1-acetyl/propyl-3-aryl-5-(5-chloro-3-methyl-1-phenyl-1H- pyrazol-4-yl)-2-pyrazolines were synthesized in one step by condensing suitably substituted propenones, hydrazine and acetic/propionic acid. The newly synthesized pyrazolines were characterized by analytical and spectral data. The new compounds were screened for analgesic and anti-inflammatory activity and most of them showed good activity comparable with that of standard drugs Pentazocin and Diclofinac sodium respectively.

Design, synthesis, and characterization of some novel pyrazolo [1,5-a] pyrimidines as potent antimicrobial agents

(Chemical Equation Presented) A novel series of pyrazolo [1,5-a] pyrimidines were synthesized by the condensation of substituted chalcones with 5-amino pyrazole in presence of dimethyl formamide. All the synthesized products were characterized by the spec