149882-16-6

Basic information

• Product Name: (S)-(+)-2-(2,4-Difluorophenyl)-3-(1,2,4-triazol-1-yl)-1,2-propanediol
• Synonyms: (S)-(+)-2-(2,4-Difluorophenyl)-3-(1,2,4-triazol-1-yl)-1,2-propanediol
• CAS NO: 149882-16-6
• Molecular Weight: 255.224
• Mol File: 149882-16-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: (S)-(+)-2-(2,4-Difluorophenyl)-3-(1,2,4-triazol-1-yl)-1,2-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-2-(2,4-Difluorophenyl)-3-(1,2,4-triazol-1-yl)-1,2-propanediol(149882-16-6)
• EPA Substance Registry System: (S)-(+)-2-(2,4-Difluorophenyl)-3-(1,2,4-triazol-1-yl)-1,2-propanediol(149882-16-6)

Safety Data

• Hazardous Substances Data: 149882-16-6(Hazardous Substances Data)

Upstream product

• 288-88-0 1,2,4-Triazole 
• 219923-95-2 3-chloro-2-(2,4-difluorophenyl)propane-1,2-diol 
• 159553-75-0 Acetic acid (S)-2-(2,4-difluoro-phenyl)-2-hydroxy-3-[1,2,4]triazol-1-yl-propyl ester 
• 348-57-2 2,4-difluorobromobenzene 
• 141113-36-2 2-(2,4-difluorophenyl)allyl alcohol 
• 164347-62-0 1,2-epoxy-3-chloro-2-(2,4-difluorophenyl)-propane 
• 86386-74-5 1,3-(dichloro)-2-(2,4-difluorophenyl)propan-2-ol 
• 141113-39-5 (S)-(2-(2,4-difluorophenyl)oxiran-2-yl)methanol 

Downstream Products

• 170985-70-3 (S)-2-(2,4-Difluorophenyl)-3-(1,2,4-triazol-1-yl)-1,2-propanediol-1-methanesulfonate 
• 141113-41-9 (R)-(-)-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1,2-diol 
• 118689-07-9 (S)-(+)-2(2,4-Difluorophenyl)-3-(1,2,4-triazol-1-yl)-1,2-propanediol 
• 141113-42-0 (S)-1-((2-(2,4-difluorophenyl)oxiran-2-yl)methyl)-1H-1,2,4-triazole 
• 149809-36-9 Toluene-4-sulfonic acid (S)-2-(2,4-difluoro-phenyl)-2-hydroxy-3-[1,2,4]triazol-1-yl-propyl ester 

Relevant articles and documents

Enantioselective Oxetane Ring Opening with Chloride: Unusual Use of Wet Molecular Sieves for the Controlled Release of HCl

An unprecedented enantioselective oxetane opening with chloride provides access to a range of highly functionalized three-carbon building blocks. The excellent enantiocontrol is enabled not only by a new catalyst, but also by the unusual use of wet molecular sieves for the controlled release of HCl. The enantioselective ring opening of oxetanes with chloride provides access to a range of highly functionalized three-carbon building blocks. The use of a new catalyst in combination with wet molecular sieves for the controlled release of HCl leads to high enantioselectivities.

Tetrahydrofuran antifungals

A compound represented by the formula I STR1 wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two amino acid ester groups (e.g., an amino acid ester group convertible in vivo into a hydroxy group) thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.

Tetrahydrofuran antifungals

A compound represented by the formula I STR1 wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two hydroxy moieties, an ether or ester thereof (e.g., a polyether ester amino acid ester or phosphate ester) thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.