149916-84-7

Upstream product

• 70542-83-5 ethyl (2E)-5-(benzyloxy)pent-2-enoate 
• 126107-76-4 (2R,3S)-3-[2-(benzyloxy)ethyl]oxiran-2-methanol 
• 4799-68-2 3-benzyloxypropan-1-ol 
• 149916-82-5 (2R,3S)-3-[2-(benzyloxy)ethyl]oxirane-2-carbaldehyde 
• 111466-55-8 ((2S,3S)-3-(2-(benzyloxy)ethyl)oxiran-2-yl)methanol 
• 100-39-0 benzyl bromide 
• 19790-60-4 3-Benzyloxypropanal 
• 89923-31-9 (E)-5-(benzyloxy)pent-2-en-1-ol 
• 75-24-1 trimethylaluminum 
• 959125-19-0 (E)-ethyl 3-((2R,3S)-3-(2-(benzyloxy)ethyl)oxiran-2-yl)acrylate 
• 149916-83-6 (E)-3-[(2S,3S)-3-(2-Benzyloxy-ethyl)-oxiranyl]-acrylic acid ethyl ester 

Downstream Products

• 201054-34-4 [(4R,5S,6S)-6-(2-Benzyloxy-ethyl)-5-methyl-2-phenyl-[1,3]dioxan-4-yl]-acetic acid ethyl ester 
• 201054-36-6 (3R,4S,5R,6S)-6-(2-Benzyloxy-ethyl)-4-hydroxy-3,5-dimethyl-tetrahydro-pyran-2-one 
• 201054-38-8 (3R,4S,5S,6S)-6-(2-Benzyloxy-ethyl)-4-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethyl-tetrahydro-pyran-2-one 
• 201054-30-0 (4R,5R,6S)-6-(2-Benzyloxy-ethyl)-4-hydroxy-5-methyl-tetrahydro-pyran-2-one 
• 149916-90-5 1-[(4R,5S,6S)-6-(2-Benzyloxy-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-ethanone 
• 149916-87-0 (4S,5S,6S)-4-(2-Benzyloxy-ethyl)-2,2,5-trimethyl-6-vinyl-[1,3]dioxane 
• 128684-70-8 (3S,4S,5S)-7-Benzyloxy-4-methyl-hept-1-ene-3,5-diol 
• 149916-85-8 (E)-(4R,5S)-7-Benzyloxy-4-methyl-hept-2-ene-1,5-diol 

Relevant academic research and scientific papers

Expeditious and stereoselective synthesis of chiral trans -β-hydroxy-δ-lactone systems

Expeditious and stereoselective synthesis of chiral trans-β-hydroxy-δ-lactone systems starting from γ,δ-epoxy acrylates is described which involves the regioselective ring opening of an epoxide and the intramolecular conjugate addition of a hemiacetal alkoxide anion of δ-hydroxy-α,β-unsaturated esters as key steps.

Stereoselective synthesis of the C1-C7 segment of (+)-discodermolide

A new and highly stereoselective synthesis of the C1-C7 segment of (+)-discodermolide, the marine natural product having the potent immunosuppressive activity, is described in which the stereospecific methylation of γ,δ-epoxy acrylat

STEREOSELECTIVE SYNTHESIS OF C-9 TO C-16 FRAGMENT OF TRIENOMYCIN BASED ON THE REGIOSELECTIVE OPENING OF γ-δ-EPOXY ACRYLATES WITH TRIMETHYLALUMINIUM

The C-9 to C-16 fragment, a key intermediate for the synthesis of a 21 membered ansamycin antibiotic, Trienomycin has been synthesized, involving Sharpless asymmetric epoxidation and the key stereoselective methylation of γ-δ-epoxy acrylates by Trimethyla