149947-16-0Relevant articles and documents
Ansa-Zirconocene Catalysts for Isotactic-Selective Propene Polymerization at High Temperature: A Long Story Finds a Happy Ending
Kulyabin, Pavel S.,Goryunov, Georgy P.,Sharikov, Mikhail I.,Izmer, Vyatcheslav V.,Vittoria, Antonio,Budzelaar, Peter H. M.,Busico, Vincenzo,Voskoboynikov, Alexander Z.,Ehm, Christian,Cipullo, Roberta,Uborsky, Dmitry V.
, p. 7641 - 7647 (2021)
Absolute rigidity is rare in the "soft"world of organometallics. Here we introduce two cyclopenta[a]triptycyl ansa-zirconocene catalysts for isotactic-selective propene polymerization, designed by means of an integrated high-throughput experimentation/qua
Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors
Cinelli, Maris A.,Li, Huiying,Chreifi, Georges,Poulos, Thomas L.,Silverman, Richard B.
supporting information, p. 3958 - 3978 (2017/05/19)
Neuronal nitric oxide synthase (nNOS) inhibition is a promising strategy to treat neurodegenerative disorders, but the development of nNOS inhibitors is often hindered by poor pharmacokinetics. We previously developed a class of membrane-permeable 2-amino
OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF
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Page/Page column 96, (2011/02/26)
The present application relates to novel carboxylic acid derivatives having an oxo-substituted azaheterocyclic partial structure, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.