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3-(Methylsulfonyl)benzamidine hydrochloride is a chemical compound with the molecular formula C8H11ClN2O2S. It is a derivative of benzamidine, which is commonly used as a protease inhibitor in biochemical research. This specific derivative features a methylsulfonyl group, enhancing its potential as an anti-inflammatory and anticoagulant agent. The hydrochloride salt form of the compound improves its solubility, making it suitable for pharmaceutical formulations. It holds promise for therapeutic applications in treating inflammatory conditions and serves as a valuable research tool in drug development and biochemistry.

150296-24-5

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150296-24-5 Usage

Uses

Used in Pharmaceutical Industry:
3-(Methylsulfonyl)benzamidine hydrochloride is used as an active pharmaceutical ingredient for its potential therapeutic applications in the treatment of inflammatory conditions. Its anti-inflammatory and anticoagulant properties make it a promising candidate for the development of new drugs targeting these conditions.
Used in Biochemical Research:
3-(Methylsulfonyl)benzamidine hydrochloride is used as a protease inhibitor in biochemical research. Its ability to inhibit proteases can help researchers study the role of these enzymes in various biological processes and diseases.
Used in Drug Development:
3-(Methylsulfonyl)benzamidine hydrochloride is used as a lead compound in drug development. Its unique properties, including the methylsulfonyl group and hydrochloride salt form, make it a valuable starting point for the design and synthesis of new drugs with improved efficacy and solubility.
Used in Anticoagulant Therapy:
3-(Methylsulfonyl)benzamidine hydrochloride is used as an anticoagulant agent. Its potential to prevent blood clot formation makes it a candidate for the development of new anticoagulant drugs, which could be used to treat and prevent conditions such as deep vein thrombosis, pulmonary embolism, and stroke.
Used in Inflammatory Disease Treatment:
3-(Methylsulfonyl)benzamidine hydrochloride is used as an anti-inflammatory agent in the treatment of inflammatory diseases. Its ability to reduce inflammation can help alleviate symptoms and prevent complications associated with various inflammatory conditions, such as arthritis, asthma, and inflammatory bowel disease.

Check Digit Verification of cas no

The CAS Registry Mumber 150296-24-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,2,9 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 150296-24:
(8*1)+(7*5)+(6*0)+(5*2)+(4*9)+(3*6)+(2*2)+(1*4)=115
115 % 10 = 5
So 150296-24-5 is a valid CAS Registry Number.

150296-24-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-methanesulfonyl-benzamidine, hydrochloride

1.2 Other means of identification

Product number -
Other names 3-(Methylsulfonyl)benzamidine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:150296-24-5 SDS

150296-24-5Relevant academic research and scientific papers

Reaction of arylhalodiazirines with thiophenoxide: A redox process

Creary, Xavier,Sky, Anthony F.,Phillips, Gillian,Alonso, David E.

, p. 7584 - 7592 (2007/10/02)

Phenylbromodiazirine reacts with thiophenoxide ion in methanol to give benzonitrile, benzamidine, ammonia, and diphenyl disulfide. The reaction is general for arylhalodiazirines, with electron-withdrawing groups on the aromatic ring exerting a small rate-enhancing effect. Three potential mechanisms are suggested for this redox process. These mechanisms include an N-sulfenylated diazirine, a diazirinyl radical, and a diazirinyl anion. Ring opening of these intermediates and subsequent transformations would lead to benzonitriles, benzamidine, and ammonia. A key intermediate in these transformations is PhSNH2, 32. This intermediate has been independently generated and found to rapidly convert to ammonia and diphenyl disulfide under the reaction conditions. Another proposed intermediate, N-(phenylthio)benzamidine, 38, has also been independently generated and subjected to the reaction conditions, where benzamidine and more diphenyl disulfide result. Theoretical calculations suggest the existence of isomeric diazirinyl anions. In addition to a diazirinyl ion with charge essentially on carbon, there is also an allylic-type ion with charge on the two nitrogen atoms. Single-electron reduction of a diazirinyl radical necessarily leads to a nitrogen-centered diazirinyl anion. Conversion of this anion to the carbon-centered diazirinyl anion is a forbidden process. These theoretical studies suggest that the diazirinyl anion may be a viable intermediate in solution.

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