150879-48-4

Basic information

• Product Name: Benzamide, 2-amino-5-chloro-N-methoxy-N-methyl-
• CAS NO: 150879-48-4
• Molecular Formula: C9H11ClN2O2
• Molecular Weight: 214.652
• Mol File: 150879-48-4.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-amino-5-chloro-N-methoxy-N-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-amino-5-chloro-N-methoxy-N-methyl-(150879-48-4)
• EPA Substance Registry System: Benzamide, 2-amino-5-chloro-N-methoxy-N-methyl-(150879-48-4)

Safety Data

• Hazardous Substances Data: 150879-48-4(Hazardous Substances Data)

Upstream product

• 635-21-2 5-chloroanthranilic acid 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 4743-17-3 5-Chloroisatoic anhydride 

Downstream Products

• 835882-20-7 (2-amino-5-chloro-phenyl)-(4-ethyl-phenyl)-methanone 
• 105192-41-4 (2-amino-5-chlorophenyl)-3-pyridinylmethanone 
• 69559-40-6 N-(2-benzoyl-4-chlorophenyl)-2,2,2-trifluoroacetamide 
• 1830-42-8 (2-amino-5-chlorophenyl)(pyridin-2-yl)methanone 
• 1000994-74-0 C₂₂H₂₂ClNO₃ 
• 1000994-73-9 C₂₂H₂₀ClNO₃ 
• 1000994-72-8 C₂₂H₂₀ClNO₃ 
• 1440430-14-7 C₂₃H₂₀ClNO₂S 
• 784-38-3 2-amino-5-chloro-2'-fluorobenzophenone 
• 76049-49-5 (5-chloro-2-iodophenyl)(2-fluorophenyl)methanone 
• 76049-50-8 2',5-dichloro-2-iodobenzophenone 
• 76049-48-4 5-chloro-2-iodobenzophenone 

Relevant articles and documents

QUINOLINONE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS

Disclosed herein are certain quinolinone derivatives of Formula (A) that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.

Catalytic Asymmetric Synthesis of Atropisomeric Quinolines through the Friedl?nder Reaction

A phosphoric acid catalyzed atroposelective Friedl?nder reaction was developed in which acetylacetone and a variety of 2′-substituted 2-Aminobenzophenones were successfully employed to give optically active biaryl quinolines in good yields and with high enantioselectivities.

Palladium-Catalyzed Cascade Reductive and Carbonylative Cyclization of Ortho-Iodo-Tethered Methylenecyclopropanes (MCPs) Using N-Formylsaccharin as CO Source

A palladium-catalyzed reductive and carbonylative cyclization of ortho-iodo-tethered methylenecyclopropanes (MCPs) using N-formylsaccharin as CO source has been developed, affording the desired indanone derivatives in moderate to good yields with high regio- and stereoselectivity and good functional group compatibility.