151239-47-3

Basic information

• Product Name: 4-BROMO-3'-METHOXYBENZOPHENONE
• Synonyms: (4-BROMOPHENYL)-(3-METHOXYPHENYL)METHANONE;4-BROMO-3'-METHOXYBENZOPHENONE
• CAS NO: 151239-47-3
• Molecular Formula: C₁₄H₁₁BrO₂
• Molecular Weight: 291.14
• Mol File: 151239-47-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 396.8°Cat760mmHg
• Flash Point: 193.8°C
• Appearance: /
• Density: 1.401g/cm³
• CAS DataBase Reference: 4-BROMO-3'-METHOXYBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-3'-METHOXYBENZOPHENONE(151239-47-3)
• EPA Substance Registry System: 4-BROMO-3'-METHOXYBENZOPHENONE(151239-47-3)

Safety Data

• Hazardous Substances Data: 151239-47-3(Hazardous Substances Data)

Usage

General Description

4-Bromo-3'-methoxybenzophenone is a chemical compound that falls into the category of benzophenones. Benzophenones are typically used as sunscreens, fragrance enhancers, or light absorbers such as in plastic manufacturing. Its molecular formula is C14H11BrO2, and it possesses unique chemical properties such as a melting point of 92-94°C, and a molecular weight of 303.14. It often appears as a grey to brown crystalline powder. The 4-bromo-3'-methoxybenzophenone compound, like other similar chemical compounds, should be handled with care due to the general health hazards associated with benzophenones, which can include skin and eye irritation and potential endocrine disruption.

Upstream product

• 1711-05-3 m-anisoyl chloride 
• 872088-07-8 4-bromophenylmagnesium iodide 
• 134446-26-7 (4-bromo-phenyl)-(3-methoxy-phenyl)-methanol 
• 1399825-49-0 C₁₄H₁₃BrO 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 586-75-4 4-chlorobenzoyl chloride 
• 192436-83-2 4-bromo-N-methoxy-N-methylbenzamide 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 280564-77-4 2-amino-1-(4-bromo-phenyl)-1-(3-methoxy-phenyl)-ethanol 
• 1357563-33-7 (4'-hydroxy-3'-methylbiphenyl-4-yl)-(3-hydroxyphenyl)-methanone 
• 1357563-34-8 (3'-fluoro-4'-hydroxybiphenyl-4-yl)-(3-hydroxyphenyl)-methanone 
• 1357563-35-9 (2'-chloro-4'-hydroxybiphenyl-4-yl)-(3-hydroxyphenyl)-methanone 
• 1357563-36-0 (3'-chloro-4'-hydroxybiphenyl-4-yl)-(3-hydroxyphenyl)-methanone 
• 1357563-67-7 (3'-chloro-4'-hydroxybiphenyl-4-yl)-(3-methoxyphenyl)-methanone 
• 1357563-63-3 (3'-fluoro-4'-methoxybiphenyl-4-yl)-(3-methoxyphenyl)-methanone 
• 1357563-62-2 (4'-methoxy-3'-methylbiphenyl-4-yl)-(3-methoxyphenyl)-methanone 
• 1357563-65-5 (2'-chloro-4'-methoxybiphenyl-4-yl)-(3-methoxyphenyl)-methanone 
• 62810-46-2 (4-bromophenyl)-(3-hydroxyphenyl)methanone 

Relevant articles and documents

Synthesis and biological evaluation of N-cyclopropylbenzamide-benzophenone hybrids as novel and selective p38 mitogen activated protein kinase (MAPK) inhibitors

A series of hybrid molecules consisting of benzophenones and N-cyclopropyl-3-methylbenzamides were synthesized and biologically evaluated as novel p38 mitogen activated protein kinase (MAPK) inhibitors. In particular, we found that compound 10g displayed

AIBN initiated functionalization of the benzylic sp3 C[sbnd]H and C[sbnd]C bonds in the presence of dioxygen

A sp3 C[sbnd]H bond functionalization and C[sbnd]C bond cleavage were realized by AIBN/O2 catalyst system, providing a series of benzophenones under mild reaction conditions. The mechanistic study shows that a peroxide intermediate is involved in this transformation, and in the case of diphenylmethanes, the sp3 C[sbnd]C bond is cleaved through the peroxide rearrangement, which might provides a new way to cleave relatively strong C[sbnd]C bond and be applied to more general C[sbnd]C bond activation.

Addition of Grignard reagents to aryl acid chlorides: An efficient synthesis of aryl ketones

(Chemical Equation Presented) Direct addition of Grignard reagents to acid chlorides in the presence of bis[2-(N,N-dimethylamino)ethyl] ether proceeds selectively to provide aryl ketones in high yields. A possible tridentate interaction between Grignard reagents and bis[2-(N,N-dimethylamino)ethyl] ether moderates the reactivity of Grignard reagents, preventing the newly formed ketones from nucleophilic addition by Grignard reagents.