1518-06-5Relevant academic research and scientific papers
Synthesis of functional 1,2-dithiolanes from 1,3-bis-: Tert -butyl thioethers
Scheutz, Georg M.,Rowell, Jonathan L.,Wang, Fu-Sheng,Abboud, Khalil A.,Peng, Chi-How,Sumerlin, Brent S.
, p. 6509 - 6513 (2020)
We report the one-step synthesis of diversely substituted functional 1,2-dithiolanes by reacting readily accessible 1,3-bis-tert-butyl thioethers with bromine. The reaction proceeds to completion within minutes under mild conditions, presumably via a sulf
Favorskii-Type Rearrangement of α,α'-Dihalo Ketones with Sodiomalonates Leading to Conjugated Enone Derivatives
Sakai, Takashi,Ishikawa, Mutsumi,Amano, Eiichiro,Utaka, Masanori,Takeda, Akira
, p. 2295 - 2297 (1987)
A new synthetic method of conjugated enones by the use of carbanion-induced Favorskii-type rearrangement is described.The reaction of α,α'-dihalo ketones R1R2-(X)CC(O)CH2X with sodiomalonates Na+-CR3(
Formation of α-iminoketones and α-diimines versus Favorskii rearrangement products from the reaction of α,α′-dibromoketones and primary amines
De Kimpe, Norbert,D'Hondt, Luc,Mones, Luc
, p. 3183 - 3208 (2007/10/02)
The reaction of aliphatic acyclic α,α'-dibromoketones with primary amines gave rise to α-iminoketones and α-diimines. Both reaction products could be selectively obtained under appropriate reaction conditions. Sterically hindered α,α-dibromoketones did no
Bromination of Enamines from Methyl Isopropyl Ketone. III. Bromination of 2-(1-Pyrrolidinyl)-3-methyl-1-butene
Carlson, Rolf
, p. 157 - 160 (2007/10/02)
The reaction of 2-(1-pyrrolidinyl)-3-methyl-1-butene with elemental bromine was studied under varying conditions.Reaction in pentane solution followed by hydrolysis afforded high yields of the expected halomethyl ketone, 1-bromo-3-methyl-2-butanone.Reaction in dichloromethane gave several by-products.Mechanisms for the by-product forming reactions are suggested and experimental observations supporting the proposed mechanisms are given.
