7290-99-5

Basic information

• Product Name: 3-methoxy-N,N-dimethylbenzamide
• Synonyms: 3-Methoxy-N,N-dimethyl-benzamide; benzamide, 3-methoxy-N,N-dimethyl-
• CAS NO: 7290-99-5
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.2157
• Mol File: 7290-99-5.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 314.4°C at 760 mmHg
• Flash Point: 144°C
• Density: 1.062g/cm³
• Vapor Pressure: 0.000467mmHg at 25°C
• Refractive Index: 1.52
• CAS DataBase Reference: 3-methoxy-N,N-dimethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxy-N,N-dimethylbenzamide(7290-99-5)
• EPA Substance Registry System: 3-methoxy-N,N-dimethylbenzamide(7290-99-5)

Safety Data

• Hazardous Substances Data: 7290-99-5(Hazardous Substances Data)

Upstream product

• 2398-37-0 3-methoxyphenyl bromide 
• 68-12-2 N,N-dimethyl-formamide 
• 586-38-9 3-Methoxybenzoic acid 
• 124-40-3 dimethyl amine 
• 766-85-8 3-methoxy-1-iodobenzene 
• 201230-82-2 carbon monoxide 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 6971-51-3 3-methoxybenzyl alcohol 
• 67-56-1 methanol 
• 1026136-89-9 N,N-dimethyl-2-tert-butylsulfinyl-3-methoxybenzamide 
• 4375-83-1 tris(dimethylamino)borane 
• 591-31-1 3-methoxy-benzaldehyde 
• 1624-01-7 tetrakis(dimethylamino)silane 

Downstream Products

• 127787-05-7 N-(Bis-trimethylsilanyl-methyl)-3-methoxy-N-methyl-benzamide 
• 15184-99-3 N,N-dimethyl-3-methoxybenzylamine 
• 15789-03-4 3-hydroxy-N,N-dimethylbenzamide 
• 56071-04-6 2-(3-methoxyphenyl)quinazolin-4(3H)-one 
• 20359-55-1 1-(3-methoxyphenyl)pentan-1-one 
• 97740-53-9 2,6-dimethyl-N-phenylbenzamide 
• 300667-15-6 methyl 4-[(3-methoxybenzoyl)amino]benzoate 
• 1369884-56-9 C₁₂H₉ClN₂O₂ 
• 568581-19-1 4-chloro-2-(3-methoxyphenyl)-5-methylfuro[2,3-d]-pyrimidine 

Relevant articles and documents

Bifunctional organocatalysts for the asymmetric synthesis of axially chiral benzamides

Bifunctional organocatalysts bearing amino and urea functional groups in a chiral molecular skeleton were applied to the enantioselective synthesis of axially chiral benzamides via aromatic electrophilic bromination. The results demonstrate the versatilit

A general continuous flow method for palladium catalysed carbonylation reactions using single and multiple tube-in-tube gas-liquid microreactors

A series of continuous flow chemistry processes that facilitate the palladium-catalysed carbonylation of aryl and vinyl iodides and aryl bromides with a range of alkoxy, hydroxy and amino nucleophiles is reported. Harnessing a semipermeable Teflon AF-2400 Tube-in-Tube assembly, these reactors permit the controlled transport of carbon monoxide into solution at elevated pressure to generate homogeneous flow streams, avoiding some potential issues associated with segmented flow gas-liquid reactors. As the volume of pressurised gas contained within the device is low, the hazards associated with this are potentially mitigated relative to comparable batch processes. We also show how the incorporation of a second in-line gas-flow reactor allows for the sequential introduction of two gases (carbon monoxide and a gaseous nucleophile) into the reaction stream. A Teflon AF-2400 Tube-in-Tube reactor facilitates the use of carbon monoxide in continuous-flow C-C bond forming reactions providing esters, amides, carboxylic acids, lactones and lactams. Two reactors can be used in series to permit the sequential addition of two reactive gases (CO and Me2NH) into the flow stream.

Oxidative synthesis of benzamides from toluenes and DMF

An interesting oxidative procedure for the synthesis of benzamides has been developed through the cleavage of sp3CH bond of methyl arenes with N-substituted formamides. Various benzamides were prepared in low to moderate yields. Even though the